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Bovine serum albumin (BSA or "Fraction V") is a serum albumin protein derived from cows. It is often used as a protein concentration standard in lab experiments. The nickname "Fraction V" refers to albumin being the fifth fraction of the original Edwin Cohn purification methodology that made use of differential solubility characteristics of plasma proteins.
The 3D structure of human serum albumin has been determined by X-ray crystallography to a resolution of 2.5 ångströms (250 pm). [1] Albumin is a 65–70 kDa protein. Albumin comprises three homologous domains that assemble to form a heart-shaped protein. [2] Each domain is a product of two subdomains that possess common structural motifs. [2]
Routine blood tests may reveal anaemia, high CRP or low albumin; which shows a high correlation for the presence of an organic disease. [ 10 ] [ 11 ] In this setting, microcytic anaemia usually implies iron deficiency and macrocytosis can be caused by impaired folic acid or B12 absorption or both.
The CKD-EPI equation performed better than the MDRD (Modification of Diet in Renal Disease Study) equation, especially at higher GFR, with less bias and greater accuracy. When looking at NHANES (National Health and Nutrition Examination Survey) data, the median estimated GFR was 94.5 mL/min per 1.73 m 2 vs. 85.0 mL/min per 1.73 m 2 , and the ...
Glycated hemoglobin (also called glycohemoglobin) is a form of hemoglobin (Hb) that is chemically linked to a sugar. ("Glycosylated haemoglobin" is a misnomer because glycation and glycosylation are different processes, of which only the former is relevant in this case.)
D site of albumin promoter (albumin D-box) binding protein, also known as DBP, is a protein which in humans is encoded by the DBP gene. [ 5 ] [ 6 ] DBP is a member of the PAR bZIP ( P roline and A cidic amino acid- R ich b asic leucine ZIP per) transcription factor family.
References range may vary with age, sex, race, pregnancy, [10] diet, use of prescribed or herbal drugs and stress. Reference ranges often depend on the analytical method used, for reasons such as inaccuracy , lack of standardisation , lack of certified reference material and differing antibody reactivity . [ 11 ]
The dog (Canis familiaris or Canis lupus familiaris) is a domesticated descendant of the wolf.Also called the domestic dog, it was selectively bred from an extinct population of wolves during the Late Pleistocene by hunter-gatherers.