Ads
related to: brain abnormalities in schizophreniaeverydayhealth.com has been visited by 10K+ users in the past month
Search results
Results from the WOW.Com Content Network
Abnormal brain connectivity has long been theorized as a fundamental cause of psychosis in schizophrenia. [21] rs-fMRI can help evaluate regional interactions at rest and whether there are altered, reduced, or hyperactive connections in psychiatric disorders like schizophrenia. During resting-state fMRI experiments, participants are instructed ...
[137] [138] [139] Post-mortem studies consistently find that a subset of these neurons fail to express GAD67 , [140] in addition to abnormalities in brain morphometry. The subsets of interneurons that are abnormal in schizophrenia are responsible for the synchronizing of neural ensembles needed during working memory tasks.
The causes of schizophrenia that underlie the development of schizophrenia, a psychiatric disorder, are complex and not clearly understood.A number of hypotheses including the dopamine hypothesis, and the glutamate hypothesis have been put forward in an attempt to explain the link between altered brain function and the symptoms and development of schizophrenia.
Abnormal expression, thus distribution of the D 2 receptor between these areas and the rest of the brain may also be implicated in schizophrenia, specifically in the acute phase. A relative excess of these receptors within the limbic system means Broca's area , which can produce illogical language, has an abnormal connection to Wernicke's area ...
Research on rodents seeking to understand the possible role of prenatal hypoxia in disorders such as schizophrenia has indicated that it can lead to a range of sensorimotor and learning/memory abnormalities. Impairments in motor function and coordination, evident on challenging tasks when the hypoxia was severe enough to cause brain damage ...
Reelin abnormalities may also be involved in the pathogenesis of schizophrenia via a glutamate-dependent mechanism. Reelin expression deficits are seen in schizophrenia, and reelin enhances expression of AMPA and NMDA alike. [8] As such deficits in these two ionotropic glutamate receptors may be partially explained by altered reelin cascades.
Ads
related to: brain abnormalities in schizophreniaeverydayhealth.com has been visited by 10K+ users in the past month