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At least 90% of cases having cryoglobulins in body, hepatitis C is to blame, [11] [13] reflecting the importance of preclusion of hepatitis C. [11] [13] The presence of cryoglobulins in body satisfies the criterion of the diagnosis of cryoglobulinemia, a disease that inflame the blood vessels and organs like kidney, nerves, joints, lungs and ...
Cryoglobulinemic vasculitis is a form of inflammation affecting the blood vessels caused by the deposition of abnormal proteins called cryoglobulins.These immunoglobulin proteins are soluble at normal body temperatures, but become insoluble below 37 °C (98.6 °F) and subsequently may aggregate within smaller blood vessels.
Since the first description of cryoglobulinemia in association with the clinical triad of skin purpura, joint pain, and weakness by Meltzer et al. in 1966, [4] [5] the percentage of cryoglobulinemic diseases described as essential cryoglobulinemia or idiopathic cryoglobulinemia (that is, cryoglobulinemic disease that is unassociated with an underlying disorder) has fallen.
Mar. 14—Hepatitis C is a liver infection caused by the hepatitis C virus. It is becoming a big public health concern in many counties, including Lawrence County, encouraging us to review some ...
Chronic hepatitis C is defined as infection with the hepatitis C virus persisting for more than six months based on the presence of its RNA. [18] Chronic infections are typically asymptomatic during the first few decades, [ 18 ] and thus are most commonly discovered following the investigation of elevated liver enzyme levels or during a routine ...
Cold agglutinin disease (CAD) is a rare autoimmune disease characterized by the presence of high concentrations of circulating cold sensitive antibodies, usually IgM and autoantibodies that are also active at temperatures below 30 °C (86 °F), [1] directed against red blood cells, causing them to agglutinate and undergo lysis. [2]
Cryoglobulins type II and III, also known as mixed cryoglobulinemia, are composed of polyclonal immunoglobulin (Ig)G and either monoclonal IgM or both with rheumatoid factor activity. The disease can present with a wide range of symptoms, from minor ones like fatigue , purpura , or arthralgia to more serious ones like glomerulonephritis and ...
“Hot Ones” is going solo. BuzzFeed announced a deal to sell First We Feast, the studio behind the popular YouTube chicken-wing-eating celebrity talk show “Hot Ones,” for $82.5 million in ...
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