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2. Nirmatrelvir/ritonavir - Wikipedia

   en.wikipedia.org/wiki/Nirmatrelvir/ritonavir

   Nirmatrelvir, the novel portion of the co-packaged medication, was first developed in the U.S. and was initially manufactured in small amounts in Groton, Connecticut, to support clinical trials, [72] but the Freiburg facility was responsible for figuring out how to mass-produce the co-packaged medication on an industrial scale. [71]

3. Nirmatrelvir - Wikipedia

   en.wikipedia.org/wiki/Nirmatrelvir

   In February 2021, Pfizer launched the company's first phase I trial of PF-07321332 (nirmatrelvir) [30] at its clinical research unit in New Haven, Connecticut. [ 29 ] A study published in March 2023 reported that treatment with nirmatrelvir within five days of initial infection reduced the risk of long COVID relative to patients who did not ...

4. US NIH launches long-COVID trials of Pfizer's Paxlovid, other ...

   www.aol.com/news/us-nih-launches-long-covid...

   The studies are designed to evaluate multiple therapies, where the first part of trial will test a longer dosing regimen of the antiviral COVID-19 drug Paxlovid to see if it improves long COVID ...

5. Treatment and management of COVID-19 - Wikipedia

   en.wikipedia.org/wiki/Treatment_and_management...

   Although several medications have been approved in different countries as of April 2022, not all countries have these medications. Patients with mild to moderate symptoms who are in the risk groups [needs update] can take nirmatrelvir/ritonavir (marketed as Paxlovid) or remdesivir, either of which reduces the risk of serious illness or ...

6. Targeted therapy may help treat moderate to severe ulcerative ...

   www.aol.com/targeted-therapy-may-help-treat...

   An anti-TL1A monoclonal antibody called tulisokibart may help people with moderate to severe ulcerative colitis achieve clinical remission, a phase 2 trial has found.

7. COVID-19 drug development - Wikipedia

   en.wikipedia.org/wiki/COVID-19_drug_development

   The COVID-19 Clinical Research Coalition has goals to 1) facilitate rapid reviews of clinical trial proposals by ethics committees and national regulatory agencies, 2) fast-track approvals for the candidate therapeutic compounds, 3) ensure standardised and rapid analysis of emerging efficacy and safety data, and 4) facilitate sharing of ...

8. List of therapeutic monoclonal antibodies - Wikipedia

   en.wikipedia.org/wiki/List_of_therapeutic...

   inflammatory bowel disease, ulcerative colitis, Crohn's disease: Actoxumab [6] mab: human: Clostridioides difficile: Clostridioides difficile colitis: Adalimumab [7] Humira: mab: human: TNF-α: Y [8] rheumatoid arthritis, Crohn's disease, plaque psoriasis, psoriatic arthritis, ankylosing spondylitis, juvenile idiopathic arthritis, hemolytic ...

9. A Cold War-era bomb shelter in Florida has new owners. What's ...

   www.aol.com/cold-war-era-bomb-shelter-100924902.html

   FORT PIERCE, Fla. — An "iron curtain" has descended here. Residents near a Cold War-era nuclear bomb shelter are wondering what the property's new owners are doing on the other side of the chain ...