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The authors came to the conclusion that no further trials of hydroxychloroquine or chloroquine for treatment of COVID-19 should be carried out. [58] On 26 April 2021, in its amended clinical management protocol for COVID-19, the Indian Ministry of Health lists hydroxychloroquine for use in patients during the early course of the disease. [23]
[73] [74] Some of the people acutely ill with COVID-19 experience deterioration of their lungs and acute respiratory distress syndrome (ARDS) and/or respiratory failure. Due to the high risk of death, urgent respiratory support including mechanical ventilation is often required in these people. [75]
To complete the preclinical stage of drug development – then be tested for safety and efficacy in an adequate number of people infected with COVID-19 (hundreds to thousands in different countries) – is a process likely to require 1–2 years for COVID-19 therapies, according to several reports in early 2020.
The most common side effect in people with COVID‑19 is nausea. [143] Side effects may include liver inflammation and an infusion-related reaction with nausea, low blood pressure, and sweating. [153] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. [154]
On 21 May, the WHO and the UN refugee agency (UNHCR) signed a new pact, an update, and expansion of a 1997 agreement, funded by the COVID-19 Solidarity Response Fund, to better protect approximately 70 million people affected by COVID-19 in low and middle-income countries with vulnerable health systems. [92]
Authorities have encouraged or mandated social distancing during the COVID-19 pandemic as it is an important method of preventing transmission of COVID-19. [citation needed] COVID-19 is much more likely to spread over short distances than long ones. COVID-19 can spread over distances longer than 2 m (6 ft) in enclosed, poorly ventilated places ...
Coronavirus diseases are caused by viruses in the coronavirus subfamily, a group of related RNA viruses that cause diseases in mammals and birds. In humans and birds, the group of viruses cause respiratory tract infections that can range from mild to lethal.
The brand was transferred to Desitin GmbH in 1993 and is sold in several European countries, in Israel, Japan, and Australia. Sultiame became established as a second-line drug for treatment of partial epilepsy in the 1960s and 1970s and was often used in combination with the established anticonvulsant phenytoin .