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Methylene blue has been described as "the first fully synthetic drug used in medicine." Methylene blue was first prepared in 1876 by German chemist Heinrich Caro. [69] Its use in the treatment of malaria was pioneered by Paul Guttmann and Paul Ehrlich in 1891. During this period before the first World War, researchers like Ehrlich believed that ...
Gross pathology of a normal brain and a brain of a patient treated with methylene blue before death in a case of vasoplegic syndrome. Vasoplegic syndrome or vasoplegia syndrome ( VPS ) is a postperfusion syndrome characterized by low systemic vascular resistance and a high cardiac output .
Brain fog is a common symptom in many illnesses where chronic pain is a major component. [26] Brain fog affects 15% to 40% of those with chronic pain as their major illness. [27] In such illnesses, pain processing may use up resources, decreasing the brain's ability to think effectively. [26]
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His doctor prescribed him antibiotics, but the medication failed to eliminate one of his most debilitating symptoms: a lasting brain fog that made it difficult for him to focus or recall information.
Brain fog during menopause could also "be related to changes in the hypothalamus at the base of the brain, which we know occurs from the decreasing levels of estrogen," Minkin says.
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