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Rarely is any soreness associated with the condition. Apart from the appearance of the lesion, there are usually no other signs or symptoms. The typical appearance of the lesion is an oval or rhomboid shaped area located in the midline of the dorsal surface of the tongue, just anterior (in front) of the sulcus terminalis.
Initially, the corners of the mouth develop a gray-white thickening and adjacent erythema (redness). [2] Later, the usual appearance is a roughly triangular area of erythema, edema (swelling) and breakdown of skin at either corner of the mouth. [2] [4] The mucosa of the lip may become fissured (cracked), crusted, ulcerated or atrophied.
Iron-deficiency anemia is mainly caused by blood loss, such as may occur during menses or gastrointestinal hemorrhage.This often results in a depapilled, atrophic glossitis, giving the tongue a bald and shiny appearance, along with pallor (paleness) of the lips and other mucous membranes a tendency towards recurrent oral ulceration, [6] and cheilosis (swelling of the lips). [7]
In a few cases a sore mouth can develop, and if so pain is sometimes made worse by toothpastes, or hot or spicy food. [7] The lesions can extend to involve the palate. [7] Plasma cell cheilitis appears as well defined, infiltrated, dark red plaque with a superficial lacquer-like glazing. [5] Plasma cell cheilitis usually involves the lower lip. [3]
The inflammation may include the perioral skin (the skin around the mouth), the vermilion border, or the labial mucosa. [1] The skin and the vermilion border are more commonly involved, as the mucosa is less affected by inflammatory and allergic reactions. [1] Cheilitis is a general term, and there are many recognized types and different causes.
Lip Licker's dermatitis can also be confused with Angular cheilitis which can present as similar symptoms around the mouth as erythema or ulcerations. The difference is, lip licker's dermatitis often spares the corner of the mouth while Angular cheilitis results in crusting at the corners of the mouth caused by irritant or allergy. [31]
Desquamative gingivitis is a descriptive clinical term, not a diagnosis. [1] Dermatologic conditions cause about 75% of cases of desquamative gingivitis, and over 95% of the dermatologic cases are accounted for by either oral lichen planus or cicatricial pemphigoid. [1]
A diagnosis can be made from clinical signs and symptoms, and treatment consists of minimizing the discomfort of symptoms. [5] It can be differentiated from herpetic gingivostomatitis by the positioning of vesicles - in herpangina, they are typically found on the posterior oropharynx, as compared to gingivostomatitis where they are typically found on the anterior oropharynx and the mouth.