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  2. Delayed hemolytic transfusion reaction - Wikipedia

    en.wikipedia.org/wiki/Delayed_hemolytic...

    An antiglobulin test, also known as a Coombs test, is a type of blood test used in immunohematology. An antiglobulin test may either be direct (e.g., "direct antiglobulin test" or "direct Coombs test"), or indirect. The direct test is designed to detect antibodies already bound to the surface of red blood cells in a clinical blood sample.

  3. Clinical pathology - Wikipedia

    en.wikipedia.org/wiki/Clinical_pathology

    If interfering substances are suspected, they may recommend alternate test methods. For example, hemolysis , icterus, lipemia , or heterophile antibodies may confound results obtained by traditional methods such as ion-selective electrodes, enzymatic assays or immunoassays .

  4. Febrile non-hemolytic transfusion reaction - Wikipedia

    en.wikipedia.org/wiki/Febrile_non-hemolytic...

    Fever of at least 39 °C, OR a rise in temperature of at least 2 °C from pre-transfusion values AND/OR other symptoms or signs, including chills (), painful muscles (), or nausea that are severe enough that the transfusion is stopped AND requires immediate medical treatment, admission to hospital, or lengthens the duration of hospital admission.

  5. Warm antibody autoimmune hemolytic anemia - Wikipedia

    en.wikipedia.org/wiki/Warm_antibody_autoimmune...

    The most common antibody isotype involved in warm antibody AIHA is IgG, though sometimes IgA is found. The IgG antibodies attach to a red blood cell, leaving their F C portion exposed with maximal reactivity at 37 °C (versus cold antibody induced hemolytic anemia whose antibodies only bind red blood cells at low body temperatures, typically 28–31 °C).

  6. Cellular adaptation - Wikipedia

    en.wikipedia.org/wiki/Cellular_adaptation

    Cellular hypertrophy is an increase in cell size and volume. If enough cells of an organ hypertrophy the whole organ will increase in size. Hypertrophy may involve an increase in intracellular protein as well as cytosol (intracellular fluid) and other cytoplasmic components.

  7. Contraction alkalosis - Wikipedia

    en.wikipedia.org/wiki/Contraction_alkalosis

    Diagnosis of contraction alkalosis is made by correlating laboratory data with clinical history and examination. Metabolic alkalosis in the presence of decreased effective circulatory volume, loop diuretic use, or other causes of intravascular depletion such as profound diarrhea should raise suspicion for contraction alkalosis as a likely etiology in the absence of other causes.

  8. Cold sensitive antibodies - Wikipedia

    en.wikipedia.org/wiki/Cold_sensitive_antibodies

    Cold agglutinins are antibodies, typically immunoglobulin M (), that are acquainted with and then binding the antigens on red blood cells, typically antigens "I" or "i" on the RBC surface, [1] in the environment in which the temperatures are lower than normal core body temperature and, thus, ends up leading to agglutinations of the red blood cells and hemolysis reaction occurring outside the ...

  9. Transfusion-associated graft-versus-host disease - Wikipedia

    en.wikipedia.org/wiki/Transfusion-associated...

    Transfusion-associated graft-versus-host disease (TA-GvHD) is a rare complication of blood transfusion, in which the immunologically competent donor T lymphocytes mount an immune response against the recipient's lymphoid tissue. [1]

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