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HPLC has many applications in both laboratory and clinical science. It is a common technique used in pharmaceutical development, as it is a dependable way to obtain and ensure product purity. [59] While HPLC can produce extremely high quality (pure) products, it is not always the primary method used in the production of bulk drug materials. [60]
For a complex engineering system containing thousands of assemblies, sub-assemblies, components, organized into several levels of indenture and with a number of possible repair decisions, LORA seeks to determine an optimal provision of repair and maintenance facilities to minimize overall system life-cycle costs.
HPLC like all chromatography, separates solutions into specific compounds based on relative chemical attraction for solvents and the column; if a compound is highly attracted to the column, it will "stick" to the column and elute very slowly, while if the compound is attracted to the solvent, it will tend to not stick to the column.
Chemical plant cost indexes are dimensionless numbers employed to updating capital cost required to erect a chemical plant from a past date to a later time, following changes in the value of money due to inflation and deflation. Since, at any given time, the number of chemical plants is insufficient to use in a preliminary or predesign estimate ...
Cost of poor quality (COPQ) or poor quality costs (PQC) or cost of nonquality, are costs that would disappear if systems, processes, and products were perfect. COPQ was popularized by IBM quality expert H. James Harrington in his 1987 book Poor-Quality Cost. [1] COPQ is a refinement of the concept of quality costs.
In process improvement efforts, quality costs tite or cost of quality (sometimes abbreviated CoQ or COQ [1]) is a means to quantify the total cost of quality-related efforts and deficiencies. It was first described by Armand V. Feigenbaum in a 1956 Harvard Business Review article.
Fuel costs such as power for operations, fuel for production; Public Utilities such as telephone service, Internet connectivity, etc. Maintenance of equipment; Office supplies and consumables; Insurance premium; Depreciation of equipment and eventual replacement costs (unless the facility has no moving parts it probably will wear out eventually)
The spot capacity (analogous to peak capacity in HPLC) can be increased by developing the plate with two different solvents, using two-dimensional chromatography. [8] The procedure begins with development of a sample loaded plate with first solvent. After removing it, the plate is rotated 90° and developed with a second solvent.
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