Ad
related to: baclofen instructions for studentsThe lowest prices on specific drugs - Family Circle
Search results
Results from the WOW.Com Content Network
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [ 8 ] [ 9 ] It may also be used for hiccups and muscle spasms near the end of life, [ 9 ] and off-label to treat alcohol use disorder [ 10 ] [ 11 ] or opioid withdrawal symptoms. [ 12 ]
The pump can be adjusted if muscle tone is worse at certain times of the day or night. The baclofen pump is most appropriate for individuals with chronic, severe stiffness or uncontrolled muscle movement throughout the body. [80] There is a small amount of evidence that baclofen pumps are effective in the short term. [69]
In 2008, Ameisen wrote a best-selling book, The End Of My Addiction, published in France as Le Dernier Verre (The Last Glass), describing his experience of curing his alcoholism with baclofen. [6] In 2007, an Italian team also showed the effectiveness and the safety of baclofen as a treatment for alcohol addiction. [7]
Baclofen, Ativan, lithium, Wellbutrin, Zoloft, and two or three others with chemical names. 2010 - 2011 Baclofen, Ativan, Zoloft. 2011 - 2015 Valium and Zoloft. 2015 - December 31, 2016 Valium. 2017 - Present Drug-free. (I sometimes still take Valium from an old prescription on plane flights and long taxi drives for nausea.
Intrathecal pumps require maintenance and need to be periodically refilled. How frequently this occurs is dependent on several factors, including drug concentration and dosage, and pump size. The refill frequency can range between one and six months for baclofen pumps. [2]
This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.
In one study, the affinity (K i) values of gabapentinoids for the α 2 δ subunit expressed in rat brain were found to be 0.05 μM for gabapentin, 23 μM for (R)-phenibut, 39 μM for (S)-phenibut, and 156 μM for baclofen. [9] Their affinities (K i) for the GABA B receptor were >1 mM for gabapentin, 92 μM for (R)-phenibut, >1 mM for (S)-phenibut.
Baclofen in my view was probably just suppressing alcohol withdrawal symptoms. Baclofen's suppression of temporary withdrawal symptoms may be being misinterpreted as being a successful treatment of alcoholism. We need to be careful about adding primary sources, especially weak primary sources and giving undue weight.
Ad
related to: baclofen instructions for studentsThe lowest prices on specific drugs - Family Circle