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  2. Stellaris (video game) - Wikipedia

    en.wikipedia.org/wiki/Stellaris_(video_game)

    Stellaris is a 4X grand strategy video game developed by Paradox Development Studio and published by Paradox Interactive. The game is highly inspired by the works of Stanisław Lem and contains numerous references to his works.

  3. Category:Video games about genetic engineering - Wikipedia

    en.wikipedia.org/wiki/Category:Video_games_about...

    Main page; Contents; Current events; Random article; About Wikipedia; Contact us

  4. Restriction modification system - Wikipedia

    en.wikipedia.org/.../Restriction_modification_system

    The restriction modification system (RM system) is found in bacteria and archaea, and provides a defense against foreign DNA, such as that borne by bacteriophages.. Bacteria have restriction enzymes, also called restriction endonucleases, which cleave double-stranded DNA at specific points into fragments, which are then degraded further by other endonucleases.

  5. Gene targeting - Wikipedia

    en.wikipedia.org/wiki/Gene_targeting

    Genetic modification usually describes the insertion of a transgene (foreign DNA, i.e. a gene from another species) into a random location within the genome. [ 13 ] [ 14 ] Gene-targeting is a specific biotechnological tool that can lead to small changes to the genome at a specific site [ 2 ] - in which case the edits caused by gene-targeting ...

  6. Genetic engineering techniques - Wikipedia

    en.wikipedia.org/wiki/Genetic_engineering_techniques

    Genetic engineering techniques allow the modification of animal and plant genomes. Techniques have been devised to insert, delete, and modify DNA at multiple levels, ranging from a specific base pair in a specific gene to entire genes. There are a number of steps that are followed before a genetically modified organism (GMO) is created.

  7. Point mutation - Wikipedia

    en.wikipedia.org/wiki/Point_mutation

    A point mutation is a genetic mutation where a single nucleotide base is changed, inserted or deleted from a DNA or RNA sequence of an organism's genome. [1] Point mutations have a variety of effects on the downstream protein product—consequences that are moderately predictable based upon the specifics of the mutation.

  8. CRISPR gene editing - Wikipedia

    en.wikipedia.org/wiki/CRISPR_gene_editing

    CRISPR gene editing (CRISPR, pronounced / ˈ k r ɪ s p ə r / (crisper), refers to a clustered regularly interspaced short palindromic repeats") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial CRISPR-Cas9 antiviral

  9. Off-target genome editing - Wikipedia

    en.wikipedia.org/wiki/Off-target_genome_editing

    In order for gene editing technologies to make the leap towards safe and widespread use in the clinic, the rate of off-target modification needs to be rendered obsolete. The safety of gene therapy treatment is of utmost concern, especially during clinical trials when off-target modifications can block the further development of a candidate ...