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STR analysis is a tool in forensic analysis that evaluates specific STR regions found on nuclear DNA. The variable (polymorphic) nature of the STR regions that are analyzed for forensic testing intensifies the discrimination between one DNA profile and another. [3] Scientific tools such as FBI approved STRmix incorporate this research technique.
The basis for the profile probability estimation for Y-STR analysis is the counting method. [4] The application of a confidence interval accounts for database size and sampling variation. The Y haplotype frequency (p) is calculated using the p = x/N formula, where x is equal to the number of times the haplotype is observed in a database ...
Enthought Canopy Logo. Enthought publishes a large portion of the code as open-source software under a BSD-style license. Enthought Canopy is a Python for scientific and analytic computing distribution and analysis environment, available for free and under a commercial license. [5] The Enthought Tool Suite open source software projects include: [6]
The canopy clustering algorithm is an unsupervised pre-clustering algorithm introduced by Andrew McCallum, Kamal Nigam and Lyle Ungar in 2000. [1] It is often used as preprocessing step for the K-means algorithm or the hierarchical clustering algorithm.
The microsatellite mutation rate in human male germ lines is five to six times higher than in female germ lines and ranges from 0 to 7 × 10 −3 per locus per gamete per generation. [3] In the nematode Pristionchus pacificus , the estimated microsatellite mutation rate ranges from 8.9 × 10 −5 to 7.5 × 10 −4 per locus per generation.
STR polymorphisms are genetic markers that may be used to identify a DNA sequence. The FBI analyses 13 specific STR loci for their database. These may be used in many areas of genetics in addition to their forensic uses. One can think of a STR multiplex system as a collection of specific STRs which are positionally conserved on a target genome.
A sequence profiling tool in bioinformatics is a type of software that presents information related to a genetic sequence, gene name, or keyword input. Such tools generally take a query such as a DNA , RNA , or protein sequence or ‘keyword’ and search one or more databases for information related to that sequence.
ROHR2 is a CAE system for pipe stress analysis from SIGMA Ingenieurgesellschaft mbH, based in Unna, Germany. The software performs both static and dynamic analysis of complex piping and skeletal structures, and runs on Microsoft Windows platform. [1] [2]