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The name isotretinoin is the same root tretinoin plus the prefix iso-. Regarding pronunciation, the following variants apply equally to both tretinoin and isotretinoin. Given that retinoic is pronounced / ˌ r ɛ t ɪ ˈ n oʊ ɪ k /, [43] [44] [42] [45] it is natural that / ˌ t r ɛ t ɪ ˈ n oʊ ɪ n / is a commonly heard pronunciation.
Isotretinoin, also known as 13-cis-retinoic acid and sold under the brand name Accutane among others, is a medication used to treat skin diseases like harlequin-type ichthyosis, and lamellar ichthyosis, and severe cystic acne or moderate acne that is unresponsive to antibiotics. [6]
Retinoic acid syndrome (RAS) is a potentially life-threatening complication observed in people with acute promyelocytic leukemia (APML) and first thought to be specifically associated with all-trans retinoic acid (ATRA) (also known as tretinoin) treatment. [1] Subsequently, so-called RAS was recognized in APML patients who had been treated with ...
Retinoic acid (simplified nomenclature for all-trans-retinoic acid) is a metabolite of vitamin A 1 (all-trans-retinol) that is required for embryonic development, male fertility, regulation of bone growth and immune function. [2]
retinol, retinal, tretinoin (retinoic acid), isotretinoin, and alitretinoin: Second generation: Synthetic analogs formulated for oral dosing. There are no topically available second generation formulations of retinoids. etretinate and its metabolite acitretin: Third generation: Retinoidal benzoic acid derivatives: adapalene, bexarotene, and ...
Why is Red Dye No. 3 bad? The petition filed by over 20 consumer advocacy groups in 2022 that argued for the removal of Red Dye No. 3 from food and dietary supplements cited studies, ...
As for the risks of too much RA during embryogenesis, the prescription drugs tretinoin (all-trans-retinoic acid) and isotretinoin (13-cis-retinoic acid), used orally or topically for acne treatment, are labeled with boxed warnings for pregnant women or women who may become pregnant, as they are known human teratogens. [31] [32]
Alitretinoin has been granted prescription rights in the UK (08/09/2008) for in chronic hand eczema as used by mouth. [5] In May 2009 the National Institute for Health and Clinical Excellence (NICE) issued preliminary guidance [6] on the use of alitretinoin for the treatment of severe chronic hand eczema in adults.
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