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Depiction of smooth muscle contraction. Muscle contraction is the activation of tension-generating sites within muscle cells. [1] [2] In physiology, muscle contraction does not necessarily mean muscle shortening because muscle tension can be produced without changes in muscle length, such as when holding something heavy in the same position. [1]
The sliding filament theory explains the mechanism of muscle contraction based on muscle proteins that slide past each other to generate movement. [1] According to the sliding filament theory, the myosin ( thick filaments ) of muscle fibers slide past the actin ( thin filaments ) during muscle contraction, while the two groups of filaments ...
Cardiac excitation-contraction coupling (Cardiac EC coupling) describes the series of events, from the production of an electrical impulse (action potential) to the contraction of muscles in the heart. [1] This process is of vital importance as it allows for the heart to beat in a controlled manner, without the need for conscious input.
A Wiggers diagram, named after its developer, Carl Wiggers, is a unique diagram that has been used in teaching cardiac physiology for more than a century. [1] [2] In the Wiggers diagram, the X-axis is used to plot time subdivided into the cardiac phases, while the Y-axis typically contains the following on a single grid: Blood pressure. Aortic ...
Consequently, this initial phase of ventricular systole is known as isovolumic contraction, also called isovolumetric contraction. [1] In the second phase of ventricular systole, the ventricular ejection phase, the contraction of the ventricular muscle has raised the pressure within the ventricle to the point that it is greater than the ...
This is the ejection stage of the cardiac cycle; it is depicted (see circular diagram) as the ventricular systole–first phase followed by the ventricular systole–second phase. [2] After ventricular pressures fall below their peak(s) and below those in the trunks of the aorta and pulmonary arteries, the aortic and pulmonary valves close ...
Since work is defined as force multiplied by displacement, the area of the graph shows the mechanical work output of the muscle. In a typical work-generating instance, the muscle shows a rapid curvilinear rise in force as it shortens, followed by a slower decline during or shortly before the muscle begins the lengthening phase of the cycle.
The papillary muscles extend from the walls of the heart to valves by cartilaginous connections called chordae tendinae. These muscles prevent the valves from falling too far back when they close. [24] During the relaxation phase of the cardiac cycle, the papillary muscles are also relaxed and the tension on the chordae tendineae is slight.
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