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Myelin basic protein (MBP) is a protein believed [weasel words] to be important in the process of myelination of nerves in the nervous system. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction . [ 5 ]
Maltose-binding protein (MBP) is a part of the maltose/maltodextrin system of Escherichia coli, which is responsible for the uptake and efficient catabolism of maltodextrins. It is a complex regulatory and transport system involving many proteins and protein complexes.
Cell Signaling Technology, Inc. (CST) is a privately held company that develops and produces antibodies, ELISA kits, ChIP kits, proteomic kits, and other related reagents used to study the cell signaling pathways that impact human health. CST maintains an in-house research program, particularly in the area of cancer research, and has published ...
17195 Ensembl ENSG00000165471 ENSMUSG00000024863 UniProt P11226 P41317 RefSeq (mRNA) NM_000242 NM_001378373 NM_001378374 NM_010776 NM_001365058 RefSeq (protein) NP_000233 NP_001365302 NP_001365303 NP_034906 NP_001351987 Location (UCSC) Chr 10: 52.77 – 52.77 Mb Chr 19: 30.21 – 30.22 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Mannose-binding lectin (MBL), also called mannan ...
A single antibody molecule has two antigen receptors and therefore contains twelve CDRs total. There are three CDR loops per variable domain in antibodies. Sixty CDRs can be found on a pentameric IgM molecule, which is composed of five antibodies and has increased avidity as a result of the collective affinity of all antigen-binding sites combined.
Antibodies and image courtesy of EnCor Biotechnology Inc. NeuN (Fox-3, Rbfox3, or Hexaribonucleotide Binding Protein-3) , a protein which is a homologue to the protein product of a sex-determining gene in Caenorhabditis elegans , is a neuronal nuclear antigen that is commonly used as a biomarker for neurons .
The complement system is a system of serum proteins that react with antigen-antibody complexes. If this reaction occurs on a cell surface, it will result in the formation of trans-membrane pores and therefore destruction of the cell. The basic steps of a complement fixation test are as follows: [1] Serum is separated from the patient.
Mechanism of class-switch recombination that allows isotype switching in activated B cells. Immunoglobulin class switching, also known as isotype switching, isotypic commutation or class-switch recombination (CSR), is a biological mechanism that changes a B cell's production of immunoglobulin from one type to another, such as from the isotype IgM to the isotype IgG. [1]
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