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  2. Antithyroid autoantibodies - Wikipedia

    en.wikipedia.org/wiki/Antithyroid_autoantibodies

    Binding of the antibody to the amino terminus of the TSH receptor shows stimulatory activity, whereas binding to residues 261-370 or 388-403 block the activity. TRAbs are present in 70–100% of Graves' disease (85–100% for activating antibodies and 75–96% for blocking antibodies) and 1–2% of normal individuals.

  3. Thyrotoxicosis factitia - Wikipedia

    en.wikipedia.org/wiki/Thyrotoxicosis_factitia

    Thyrotoxicosis factitia (alimentary thyrotoxicosis, exogenous thyrotoxicosis) [1] [2] is a condition of thyrotoxicosis caused by the ingestion [3] of exogenous thyroid hormone. [4] [5] It can be the result of mistaken ingestion of excess drugs, such as levothyroxine [6] and triiodothyronine, [7] or as a symptom of Munchausen syndrome.

  4. Hashimoto's thyroiditis - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_thyroiditis

    Later on in the same year, researchers from the Middlesex Hospital in London were able to perform human experiments on patients who presented with similar symptoms. They purified anti-thyroglobulin antibody from their serum and were able to conclude that these sick patients had an immunological reaction to human thyroglobulin. [4]

  5. Subacute thyroiditis - Wikipedia

    en.wikipedia.org/wiki/Subacute_thyroiditis

    The diagnosis of subacute thyroiditis can be made clinically by eliciting risk factors, associated symptoms, and physical examination. [1] [2] [3] Further work-up to differentiate between the etiologies of subacute thyroiditis can include: thyroid function tests (TFTs), inflammatory markers, complete blood count (CBC), and thyroid antibodies.

  6. Thyroid disease - Wikipedia

    en.wikipedia.org/wiki/Thyroid_disease

    Thyroid disease is a medical condition that affects the function of the thyroid gland.The thyroid gland is located at the front of the neck and produces thyroid hormones [1] that travel through the blood to help regulate many other organs, meaning that it is an endocrine organ.

  7. Graves' disease - Wikipedia

    en.wikipedia.org/wiki/Graves'_disease

    About 25 to 30% of people with the condition develop eye problems. [1] [4] The exact cause of the disease is unclear, but symptoms are a result of antibodies binding to receptors on the thyroid causing over-expression of thyroid hormone. [3] Persons are more likely to be affected if they have a family member with the disease. [1]

  8. De Quervain's thyroiditis - Wikipedia

    en.wikipedia.org/wiki/De_Quervain's_thyroiditis

    De Quervain's thyroiditis, also known as subacute granulomatous thyroiditis or giant cell thyroiditis, is a self-limiting inflammatory illness of the thyroid gland. [1] De Quervain thyroiditis is characterized by fever, flu-like symptoms, a painful goiter, and neck pain.

  9. Thyroglobulin - Wikipedia

    en.wikipedia.org/wiki/Thyroglobulin

    Thyroglobulin (Tg) is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Tg is secreted and accumulated at hundreds of grams per litre in the extracellular compartment of the thyroid follicles, accounting for approximately half of the protein content of the thyroid gland ...

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