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  2. 3-Indolepropionic acid - Wikipedia

    en.wikipedia.org/wiki/3-indolepropionic_acid

    3-Indolepropionic acid (IPA), or indole-3-propionic acid, has been studied for its therapeutic value in the treatment of Alzheimer's disease.As of 2022 [3] IPA shows potential in the treatment of this disease, though the therapeutic effect of IPA depends on dose and time of therapy initiation.

  3. Posterior cortical atrophy - Wikipedia

    en.wikipedia.org/wiki/Posterior_cortical_atrophy

    Posterior cortical atrophy (PCA), also called Benson's syndrome, is a rare form of dementia which is considered a visual variant or an atypical variant of Alzheimer's disease (AD). [ 1 ] [ 2 ] [ 3 ] The disease causes atrophy of the posterior part of the cerebral cortex , resulting in the progressive disruption of complex visual processing . [ 4 ]

  4. Experimental models of Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Experimental_models_of...

    Alzheimer's disease is a progressive neurodegenerative disorder associated with aging, which occurs both sporadically (the most common form of diagnosis) or due to familial passed mutations in genes associated with Alzheimer's pathology. [1] [2] Common symptoms associated with Alzheimer's disease include: memory loss, confusion, and mood ...

  5. HEPPS (buffer) - Wikipedia

    en.wikipedia.org/wiki/HEPPS_(buffer)

    HEPPS (EPPS) is a buffering agent used in biology and biochemistry.The pKa of HEPPS is 8.00. It is ones of Good's buffers. [1]Research on mice with Alzheimer's disease-like amyloid beta plaques has shown that HEPPS can cause the plaques to break up, reversing some of the symptoms in the mice.

  6. Protein kinase A - Wikipedia

    en.wikipedia.org/wiki/Protein_kinase_A

    In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase [1] whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA is also known as cAMP-dependent protein kinase (EC 2.7.11.11). PKA has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.

  7. Biochemistry of Alzheimer's disease - Wikipedia

    en.wikipedia.org/wiki/Biochemistry_of_Alzheimer's...

    The biochemistry of Alzheimer's disease, the most common cause of dementia, is not yet very well understood. Alzheimer's disease (AD) has been identified as a proteopathy : a protein misfolding disease due to the accumulation of abnormally folded amyloid beta (Aβ) protein in the brain . [ 1 ]

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