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Varenicline, sold under the brand names Chantix and Champix among others, is a medication used for smoking cessation [5] [7] and for the treatment of dry eye syndrome. [6] [8] It is a nicotinic acetylcholine receptor partial agonist.
Second, they are based on direct, experimentally determined values for transfer free energies of polypeptides. Two whole-residue hydrophobicity scales have been measured: One for the transfer of unfolded chains from water to the bilayer interface (referred to as the Wimley–White interfacial hydrophobicity scale).
The composition of a mixture of N absorbing species can be found by measuring the absorbance at N wavelengths (the values of the molar absorption coefficient for each species at these wavelengths must also be known). The wavelengths chosen are usually the wavelengths of maximum absorption (absorbance maxima) for the individual species.
It is also called n-octanol-water partition ratio. [2] [3] [4] K ow serves as a measure of the relationship between lipophilicity (fat solubility) and hydrophilicity (water solubility) of a substance. The value is greater than one if a substance is more soluble in fat-like solvents such as n-octanol, and less than one if it is more soluble in ...
Lisdexamfetamine is available as the dimesylate salt in the form of both oral capsules and chewable tablets. [7] A dose of 50 mg of lisdexamfetamine dimesylate is approximately equimolar to a 20 mg dose of dextroamphetamine sulfate or to 15 mg dextroamphetamine free-base in terms of the amount of dextroamphetamine contained.
[76] [77] [1] [78] Inhibition of ovulation occurred in about 90% of women at a dose of 0.5 to 2 mg/day and in 100% of women at a dose of 3 mg/day. [79] The total endometrial transformation dose of drospirenone is about 50 mg per cycle, whereas its daily dose is 2 mg for partial transformation and 4 to 6 mg for full transformation.
The tissue response (y-axis) to an agonist, in log concentration (x-axis), in the presence of different antagonist concentrations. The EC 50 of the agonist is represented by the x co-ordinate that corresponds with the half-maximum of the leftmost curve.
Adderall and Mydayis [11] are trade names [note 2] for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [13]