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Ponazuril (), sold by Merial, Inc., [1] now part of Boehringer Ingelheim, [2] under the trade name Marquis (15% w/w ponazuril), is a drug currently approved for the treatment of equine protozoal myeloencephalitis (EPM) in horses, caused by coccidia Sarcocystis neurona.
This lack of a cure or vaccine is a definite problem in the equine industry, especially in developing countries where equines are highly valuable for both agriculture and transportation. [5] Dourine is considered an endemic problem in developing countries, where over sixty percent of equines in the world are located. [ 4 ]
ATCvet code QI05 Immunologicals for equidae is a therapeutic subgroup of the Anatomical Therapeutic Chemical Classification System for veterinary medicinal products, a system of alphanumeric codes developed by the World Health Organization (WHO) for the classification of drugs and other medical products for veterinary use.
Multiple vaccines are available (Duvaxyn EHV1,4, EquiGuard, EquiVac EHV-1/4, etc.), most in an inactivated virus form. [4] The Equine Herpesvirus occupies the horse in such a way that allows post infection viral persistency over the lifetime of an animal. These carrier horses may comprise up to half of a given horse population.
The first-ever needle-free alternative to the EpiPen and similar epinephrine autoinjectors has been approved by the Food and Drug Administration to treat anaphylaxis. Neffy, a nasal spray that ...
Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors , which is used in the prevention and treatment of acute rejection in organ transplantation and therapy of aplastic anemia due to bone marrow insufficiency.
Polysulfated glycosaminoglycan (PSGAG), sold under the brand name Adequan, is an injectable drug for dogs and horses that is used to alleviate the limpness, pain, and lowered range of motion caused by arthritis. [2]
A vaccine is available, called "Chinese Live Attenuated EIA vaccine", developed in China and widely used there since 1983. Another attenuated live virus vaccine is in development in the United States. [5] Reuse of syringes and needles is a risk factor for transfer of the disease.
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