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Recent studies have used fMRI to explore specific brain networks, such as the salience network and default mode network, to understand their roles in schizophrenia-related symptoms. Alterations in these networks may affect self-referential thoughts and responses to external stimuli, potentially contributing to symptoms like hallucinations and ...
Visual processing abnormalities in schizophrenia are commonly found, and contribute to poor social function. [ 1 ] There is evidence that schizophrenia affects perception of contrast and motion , control of eye movements , detection of visual contours, and recognition of faces or facial expressions .
For instance, individuals with schizophrenia without blunted affect show activation in the following brain areas when shown emotionally negative pictures: midbrain, pons, anterior cingulate cortex, insula, ventrolateral orbitofrontal cortex, anterior temporal pole, amygdala, medial prefrontal cortex and extrastriate visual cortex.
Over the years, researchers had found that in people with schizophrenia, important parts of the brain are larger than usual, including the prefrontal cortex, which controls decision-making. Gray matter—the neural connections on which electrical signals travel, forming thoughts and emotions—is thinner.
The primary treatment of schizophrenia is the use of antipsychotic medications, often in combination with psychosocial interventions and social supports. [ 27 ] [ 185 ] Community support services including drop-in centers, visits by members of a community mental health team , supported employment , [ 186 ] and support groups are common.
Various brain stimulation techniques have been used to treat the positive symptoms of schizophrenia, in particular auditory verbal hallucinations (AVHs), and investigations are ongoing. [168] Most studies focus on transcranial direct-current stimulation (tDCM), and repetitive transcranial magnetic stimulation (rTMS). [ 169 ]
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