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[19] [20] This technique is used mainly by the Fibroscan system, which is used for liver assessment, [21] for example, to diagnose cirrhosis. [22] A specific implementation of 1D transient elastography called VCTE has been developed to assess average liver stiffness which correlates to liver fibrosis assessed by liver biopsy.
FibroTest, known as FibroSure in the US, is a biomarker test that uses the results of six blood serum tests to generate a score that is correlated with the degree of liver damage in people with a variety of liver diseases. FibroTest has the same prognostic value as a liver biopsy.
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The test results correspond to stages F0-F4 and grades A0-A3 of the METAVIR scoring system. [20] In 2007 FibroTest was validated by French Health Authorities as a first-line diagnosis of liver injury before biopsy. It was recommended to be a better predictor than biopsy staging for hepatitis C complications and death. [21]
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The NICE advises regular screening of NAFLD for advanced liver fibrosis every three years to adults and every two years for children using the enhanced liver fibrosis (ELF) blood test. [66] Follow-up is recommended for people with obesity and insulin resistance using the homeostasis model assessment of insulin resistance (HOMA-IR).
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