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Progression-free survival (PFS) is "the length of time during and after the treatment of a disease, such as cancer, that a patient lives with the disease but it does not get worse". [1] In oncology, PFS usually refers to situations in which a tumor is present, as demonstrated by laboratory testing, radiologic testing, or clinically. Similarly ...
In 1973, Mayo Clinic bought the first CT scanner in the U.S. [82] Mayo Clinic and Roche Molecular Biochemicals developed a rapid DNA test in 2001 to detect anthrax in humans and in the environment. [83] The Mayo Clinic Center for Innovation, was established in 2008 and has since worked on over 270 projects. [84] [85]
CT and MRI are the best currently available and reproducible methods to measure target lesions selected for response assessment. Conventional CT and MRI should be performed with cuts of 10 mm or less in slice thickness contiguously. Spiral CT should be performed using a 5 mm contiguous reconstruction algorithm.
Clinical monitoring is the oversight and administrative efforts that monitor a participant's health and efficacy of the treatment during a clinical trial.Both independent and government-run grant-funding agencies, such as the National Institutes of Health (NIH) [1] and the World Health Organization (WHO), [2] require data and safety monitoring protocols for Phase I and II clinical trials ...
An Australian study of 10.9 million people reported that the increased incidence of cancer after CT scan exposure in this cohort was mostly due to irradiation. In this group, one in every 1,800 CT scans was followed by an excess cancer. If the lifetime risk of developing cancer is 40% then the absolute risk rises to 40.05% after a CT.
Clinical endpoints or clinical outcomes are outcome measures referring to occurrence of disease, symptom, sign or laboratory abnormality constituting a target outcome in clinical research trials. The term may also refer to any disease or sign that strongly motivates withdrawal of an individual or entity from the trial, then often termed a ...
There are efforts to define core sets of patient-relevant outcome variables to be measured in clinical trials in general [28] and for multi-modal pain therapy. [29] Meanwhile, a core outcome measure set based on PROMS was developed with routine data and validated for operationalizing success in multimodal pain therapy. [ 30 ]
Based in the Mayo Clinic's main facility in Rochester, MN, [1] the CFI has more than 50 full-time staff including service designers, project managers, information technology specialists, and clinicians working together to develop health care delivery solutions for Mayo's Clinic's 64,000 employees and half a million patients annually in ...