Search results
Results from the WOW.Com Content Network
An example of nucleophilic substitution is the hydrolysis of an alkyl bromide, R-Br under basic conditions, where the attacking nucleophile is hydroxyl (OH −) and the leaving group is bromide (Br −). + + Nucleophilic substitution reactions are common in organic chemistry.
In chemistry, S N i (substitution nucleophilic internal) refers to a specific, regio-selective but not often encountered reaction mechanism for nucleophilic aliphatic substitution. The name was introduced by Cowdrey et al. in 1937 to label nucleophilic reactions which occur with retention of configuration, [ 1 ] but later was employed to ...
Hydrolysis (/ h aɪ ˈ d r ɒ l ɪ s ɪ s /; from Ancient Greek hydro- 'water' and lysis 'to unbind') is any chemical reaction in which a molecule of water breaks one or more chemical bonds. The term is used broadly for substitution, elimination, and solvation reactions in which water is the nucleophile. [1]
Ammonolysis refers to solvolysis by ammonia, but can also describe nucleophilic attack by ammonia more generally. Ammonia boils at −33 °C, and, as such, is rarely used as a solvent in its pure form. It is, however, readily miscible with water, and is commonly used in the form of a saturated aqueous solution. For this reason, ammonolysis may ...
It is a light yellow crystalline solid that is soluble in water. Also known as 1,3-diazanaphthalene, quinazoline received its name from being an aza derivative of quinoline . Though the parent quinazoline molecule is rarely mentioned by itself in technical literature, substituted derivatives have been synthesized for medicinal purposes such as ...
Main page; Contents; Current events; Random article; About Wikipedia; Contact us
Vinyl, aryl and tertiary alkyl halides are unreactive; as a result, the reaction of NaI in acetone can be used as a qualitative test to determine which of the aforementioned classes an unknown alkyl halide belongs to, with the exception of alkyl iodides, as they yield the same product upon substitution.
The ANRORC mechanism in organic chemistry describes a special type of substitution reaction.ANRORC stands for Addition of the Nucleophile, Ring Opening, and Ring Closure in nucleophilic attack on ring systems [1] [2] [3] and it helps to explain product formation and distribution in some nucleophilic substitutions especially in heterocyclic compounds.