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Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. [1] It is used to treat chronic obstructive pulmonary disease (COPD) and asthma . [ 2 ]
5.4 Unknown duration of action. 6 Research. 7 Society and culture. 8 See also. 9 References. 10 External links. Toggle the table of contents. Beta 2-adrenergic ...
Theophylline has also been marketed in combination with other ephedrine-like sympathomimetics like racephedrine and pseudoephedrine and with other barbiturates such as amobarbital and butabarbital, among other drugs. [15] A combination of theophylline, ephedrine, and hydroxyzine has been marketed under the brand name Marax among others as well.
Dimenhydrinate is a theoclate salt composed of diphenhydramine and 8-chlorotheophylline (a theophylline relative) in a 1:1 ratio. [2] Dimenhydrinate was introduced to the market by G.D. Searle in 1949. [3] [4]
With the exception of formoterol, LABAs are not recommended for the treatment of acute asthma exacerbations because of their slower onset of action compared to salbutamol. Their long duration of action is due to the addition of a long lipophilic side-chain that binds to an exosite on adrenergic receptors.
Time interval between drug dose administrations. Design parameter 24 h Maximum serum concentration: The peak plasma concentration of a drug after administration. / Direct measurement 60.9 mmol/L Minimum time for Cmax
Onset of action is the duration of time it takes for a drug's effects to come to prominence upon administration. With oral administration , it typically ranges anywhere from 20 minutes to over an hour, depending on the drug in question.
In recreational psychoactive drug spaces, duration refers to the length of time over which the subjective effects of a psychoactive substance manifest themselves. Duration can be broken down into 6 parts: (1) total duration (2) onset (3) come up (4) peak (5) offset and (6) after effects.