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Theophylline, also known as 1,3-dimethylxanthine, is a drug that inhibits phosphodiesterase and blocks adenosine receptors. [1] It is used to treat chronic obstructive pulmonary disease (COPD) and asthma . [ 2 ]
Available in oral and injectable form, theophylline is a long-acting bronchodilator that prevents asthma episodes. It belongs to the chemical class methylxanthines (along with caffeine). It is prescribed in severe cases of asthma or those that are difficult to control.
A mouse study on the potentiating effects of methylxanthines coadministered with mitomycin C on teratogenicity reported the incidence of birth defects for caffeine, theophylline, and paraxanthine to be 94.2%, 80.0%, and 16.9%, respectively; additionally, average birth weight decreased significantly in mice exposed to caffeine or theophylline ...
[16] [17] [18] Combinations of theophylline, ephedrine, and a barbiturate were later phased out in favor of combinations of theophylline and ephedrine alone (e.g., brand name Franol). [ 2 ] [ 1 ] Fixed-dose combinations of theophylline and ephedrine were abandoned after the 1970s as they did not allow for dose titration in asthma therapy owing ...
Because one of the active ingredients in Tedral is theophylline, Tedral is contraindicated if the patient has: [3] [6] Hypersensitivity to xanthine derivatives; Coronary artery disease (cardiac stimulating effects of Theophylline may prove harmful) Peptic ulcer; Concomitant use with ephedrine in children.
How long does COVID-19 last? Depending on whether you’ve experienced a mild or severe case of COVID-19, recovery times will vary. When it comes to mild cases of COVID-19, “in general, we would ...
How long gravy will last after Thanksgiving. Gravy can last up to four days in fridge and up to four months in freezer. To easily reheat gravy, add to a sauce pan and bringing to a rolling boil.
Theophylline (4%): Relaxes smooth muscles of the bronchi, and is used to treat asthma. The therapeutic dose of theophylline, however, is many times greater than the levels attained from caffeine metabolism. [46] 1,3,7-Trimethyluric acid is a minor caffeine metabolite. [5] 7-Methylxanthine is also a metabolite of caffeine.
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related to: how long does theophylline last in humans- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
Ranked at No. 20 on the 2020 Disruptor 50 list. - CNBC