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  2. HMG-CoA reductase - Wikipedia

    en.wikipedia.org/wiki/HMG-CoA_reductase

    This enzyme is the target of the widely available cholesterol-lowering drugs known collectively as the statins, which help treat dyslipidemia. HMG-CoA reductase is anchored in the membrane of the endoplasmic reticulum , and was long regarded as having seven transmembrane domains, with the active site located in a long carboxyl terminal domain ...

  3. Discovery and development of statins - Wikipedia

    en.wikipedia.org/wiki/Discovery_and_development...

    The primary goal was to inhibit the cholesterol biosynthesis in the body. Hence HMG-CoA reductase (HMGR) became a natural target. HMGR was found to be the rate-limiting enzyme in the cholesterol biosynthetic pathway. There is no build-up of potentially toxic precursors when HMGR is inhibited, because hydroxymethylglutarate is water-soluble and ...

  4. You can lower your cholesterol by up to 25% with diet and ...

    www.aol.com/finance/lower-cholesterol-25-diet...

    It’s a bulk-forming laxative (and the main ingredient in over-the-counter remedies like Metamucil), a prebiotic, and, according to a 2017 review, can help decrease LDL (bad) cholesterol by up to ...

  5. Lipid metabolism - Wikipedia

    en.wikipedia.org/wiki/Lipid_metabolism

    Lipid metabolism is the synthesis and degradation of lipids in cells, involving the breakdown and storage of fats for energy and the synthesis of structural and functional lipids, such as those involved in the construction of cell membranes.

  6. 7-Day Anti-Inflammatory Meal Plan to Help Lower Cholesterol ...

    www.aol.com/lifestyle/7-day-anti-inflammatory...

    Breakfast (398 calories) 1 serving Lemon-Blueberry Overnight Oats. 1 cup low-fat plain kefir. A.M. Snack (205 calories) 1 (5.3-oz.) container nonfat plain strained Greek-style yogurt

  7. 19 All-Time Favorite Breakfasts to Help Lower Your Cholesterol

    www.aol.com/19-time-favorite-breakfasts-help...

    To help keep both types of cholesterol in check, these highly rated breakfast recipes contain at least 6 grams of fiber per serving and are lower in saturated fat.

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