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The biology of depression is the attempt to identify a biochemical origin of depression, as opposed to theories that emphasize psychological or situational causes. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD) . [ 1 ]
Depression is often highly comorbid with other diseases, e.g. cardiovascular disease (myocardial infarction, [13] stroke), [14] diabetes, [15] cancer, [16] Depressed subjects are prone to smoking, [17] substance abuse, [18] eating disorders, obesity, high blood pressure, pathological gambling and internet addiction, [19] and on average have a ...
Substance abuse, especially long-term abuse, can cause or exacerbate many mental disorders. Alcoholism is linked to depression while abuse of amphetamines and LSD can leave a person feeling paranoid and anxious. Correlations of mental disorders with drug use include cannabis, alcohol, and caffeine.
There may also be imbalances in mood-regulating neurotransmitters (brain chemicals) like dopamine and serotonin. But this isn’t well understood, either. ... Illicit drug use and substance abuse.
For years, a chemical imbalance of serotonin has been widely viewed as the culprit for depression, resulting in the widespread use of antidepressants. The study published this week in the journal…
The mechanism of alcohol-related psychosis is due to distortions to neuronal membranes, gene expression, as well as thiamine deficiency. It is possible in some cases that alcohol abuse via a kindling mechanism can cause the development of a chronic substance-induced psychotic disorder (e.g., schizophrenia).
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