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Sertoli cells function to nourish the developing sperm cells. They secrete androgen-binding protein, a binding protein which increases the concentration of testosterone. There are two types: convoluted and straight, convoluted toward the lateral side, and straight as the tubule comes medially to form ducts that will exit the testis.
Thus, spermatogenesis is the male version of gametogenesis, of which the female equivalent is oogenesis. In mammals it occurs in the seminiferous tubules of the male testes in a stepwise fashion. Spermatogenesis is highly dependent upon optimal conditions for the process to occur correctly, and is essential for sexual reproduction.
Animation of the migration of spermatozoa from their origin as germ cells to their exit from the vas deferens.A) Blood vessels; B) Head of epididymis; C) Efferent ductules; D) Seminiferous tubules; E) Parietal lamina of tunica vaginalis; F) Visceral lamina of tunica vaginalis; G) Cavity of tunica vaginalis; H) Tunica albuginea; I) Lobule of testis; J) Tail of epididymis; K) Body of epididymis ...
Because its main function is to nourish developing sperm cells through the stages of spermatogenesis, the Sertoli cell has also been called the "mother" or "nurse" cell. [10] Sertoli cells also act as phagocytes, consuming the residual cytoplasm during spermatogenesis. Translocation of cells from the basal lamina to the lumen of the ...
The release of FSH into the testes will enhance spermatogenesis and lead to the development of Sertoli cells, which act as nursing cells where spermatids will go to mature after meiosis II. LH promotes Leydig cell secretion of testosterone into the testes and blood, which induce spermatogenesis and aid the formation of secondary sex ...
Spermatogenesis is a very regulated process controlled by endocrine stimuli. These stimuli include the follicle-stimulating hormone (FSH) and the luteinizing hormone (LH), which stimulate testosterone. These hormones produce regulatory signals that control the maintenance and nutrients needed for the developing germ cells.
The cremaster muscle's function is to raise and lower the testes in order to regulate scrotal temperature for optimal spermatogenesis and survival of the resultant spermatozoa. The ideal temperature for human sperm development is around 34 degrees Celsius, which is about 4 degrees Celsius below body temperature. [ 3 ]
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.