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When a non-competitive inhibitor is added the Vmax is changed, while the Km remains unchanged. According to the Lineweaver-Burk plot the Vmax is reduced during the addition of a non-competitive inhibitor, which is shown in the plot by a change in both the slope and y-intercept when a non-competitive inhibitor is added. [8]
In acoustics, Stokes's law of sound attenuation is a formula for the attenuation of sound in a Newtonian fluid, such as water or air, due to the fluid's viscosity.It states that the amplitude of a plane wave decreases exponentially with distance traveled, at a rate α given by = where η is the dynamic viscosity coefficient of the fluid, ω is the sound's angular frequency, ρ is the fluid ...
For example, an inhibitor might compete with substrate A for the first binding site, but be a non-competitive inhibitor with respect to substrate B in the second binding site. [26] Traditionally reversible enzyme inhibitors have been classified as competitive, uncompetitive, or non-competitive, according to their effects on K m and V max. [14]
Many electric guitar players intentionally overdrive their amplifiers (or insert a "fuzz box") to cause clipping in order to get a desired sound (see guitar distortion).. Some audiophiles believe that the clipping behavior of vacuum tubes with little or no negative feedback is superior to that of transistors, in that vacuum tubes clip more gradually than transistors (i.e. soft clipping, and ...
If the inhibitor is different from the substrate, then competitive inhibition will increase Km while Vmax remains the same, and non-competitive will decrease Vmax while Km remains the same. However, under substrate inhibiting effects where two of the same substrate molecules bind to the active sites and inhibitory sites, the reaction rate will ...
Electric bass players often use compression effects, either effects units available in pedal, rackmount units, or built-in devices in bass amps, to even out the sound levels of their basslines. Gain pumping , where a regular amplitude peak (such as a kick drum) causes the rest of the mix to change in volume due to the compressor, is generally ...
Credit - Getty Images. V irus season means lots of sniffles, coughs, and fevers—most of which you can treat at home. But when should you drag yourself out of bed to consult a doctor? “Going to ...
Competitive inhibition can be overcome by adding more substrate to the reaction, which increases the chances of the enzyme and substrate binding. As a result, competitive inhibition alters only the K m, leaving the V max the same. [3] This can be demonstrated using enzyme kinetics plots such as the Michaelis–Menten or the Lineweaver-Burk plot.