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Size of a normal pig kidney (left) compared to a solitary pig kidney (right). Compensatory growth is a type of regenerative growth that can take place in a number of human organs after the organs are either damaged, removed, or cease to function. [1] Additionally, increased functional demand can also stimulate this growth in tissues and organs. [2]
Most recently, the kidney has been found to have the ability to regenerate. Following removal or incapacitation of one kidney the other may double in size in order to counteract the loss of the other kidney. This is known a compensatory growth. [18] Induced regeneration stimulated by an outside source of a "non-regenerative" organ. [2]
Skin tissue can be regenerated in vivo or in vitro. Other organs and body parts that have been procured to regenerate include: penis, fats, vagina, brain tissue, thymus, and a scaled down human heart. One goal of scientists is to induce full regeneration in more human organs. There are various techniques that can induce regeneration.
The existing epithelial cells can replicate, and, using the basement membrane as a guide, eventually bring the kidney back to normal. After regeneration is complete, the damage is undetectable, even microscopically. [citation needed] Healing must happen by repair in the case of injury to cells that are unable to regenerate (e.g. neurons).
Skin grafting, invented in the late 19th century, can be thought of as the earliest major attempt to recreate bodily tissue to restore structure and function. [11] Advances in transplanting body parts in the 20th century further pushed the theory that body parts could regenerate and grow new cells.
[2] [3] [4] Regeneration can either be complete [5] where the new tissue is the same as the lost tissue, [5] or incomplete [6] after which the necrotic tissue becomes fibrotic. [ 6 ] At its most elementary level, regeneration is mediated by the molecular processes of gene regulation and involves the cellular processes of cell proliferation ...
Implantation of stem cells from culture into an existing tissue structure; Implantation of stem cells into a tissue scaffold that guides restoration; Induction of residual cells of a tissue structure to regenerate the necessary body part; A salamander can not only regenerate a limb, but can regenerate the lens or retina of an eye and can ...
In the case of wounded fetal tissue, however, wounded tissue is replaced with normal tissue through the activity of stem cells. [69] A possible method for tissue regeneration in adults is to place adult stem cell "seeds" inside a tissue bed "soil" in a wound bed and allow the stem cells to stimulate differentiation in the tissue bed cells.
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