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"The best way to monitor for a grapefruit medication interaction is to look out for the side effects of the drug," says Peterson "They should be listed in your paperwork from your prescription and ...
The effects last because grapefruit-mediated inhibition of drug metabolizing enzymes, like CYP3A4, is irreversible; [30] that is, once the grapefruit has "broken" the enzyme, the intestinal cells must produce more of the enzyme to restore their capacity to metabolize drugs that the enzyme is used to metabolize. [19]
The effects of grapefruit last from 3–7 days, with the greatest effects when juice is taken an hour previous to administration of the drug. [25] In addition to grapefruit, other fruits have similar effects. Noni (Morinda citrifolia), for example, is a dietary supplement typically consumed as a juice and also inhibits CYP3A4. [26]
Common side effects of testosterone include acne, swelling, and breast enlargement in men. [9] Serious side effects may include liver toxicity, heart disease, and behavioral changes. [9] Women and children who are exposed may develop masculinization. [9] It is recommended that individuals with prostate cancer should not use the medication. [9]
Important: If you're taking statins or medications for conditions like high blood pressure, cholesterol, heart arrhythmia, organ transplants, or allergies, it can be dangerous to eat grapefruit.
[4] [1] [5] It has also been used to treat breast cancer in women. [6] It is given by injection into muscle usually once every two to three days. [5] [7] [8] Side effects of testosterone propionate include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire. [5]
A single glass of grapefruit juice can interfere with your body's ability to break down a medication. Here's how to protect your health.
One major concern is that grapefruit can interact with certain medications, including some statins and anti-anxiety drugs, leading to dangerous side effects. Grapefruit contains compounds that can ...