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Silibinin (), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others.
Milk thistle is believed to give some remedy for liver diseases (e.g. viral hepatitis) and the extract, silymarin, is used in medicine. Mild gastrointestinal distress is the most common adverse event reported for milk thistle. The incidence is the same as for placebo. [10] A laxative effect for milk thistle has also been reported infrequently. [11]
Silybum marianum is a species of thistle.It has various common names including milk thistle, [1] blessed milkthistle, [2] Marian thistle, Mary thistle, Saint Mary's thistle, Mediterranean milk thistle, variegated thistle and Scotch thistle (not to be confused with Onopordum acanthium or Cirsium vulgare).
Flavonolignans identified in Silybum marianum (milk thistle) silymarin complex include silibinin, silychristin, silydianin, dehydrosilybin, deoxysilycistin, deoxysilydianin, silandrin, silybinome, silyhermin and neosilyhermin and can be produced in vitro. [1] Silibinin is found in the roots of S. marianum [2] while silyamandin [3] can be found ...
The Milk Thistle, also known as silymarin, has been used to treat liver or gallbladder problems. While not confirmed by the U.S. Department of Health and Human services, milk thistle has shown beneficial results in previous studies for people with HCV. It is possible that milk thistle can lower blood sugar levels for type two diabetes.
That's because cow's milk—yes, not almond milk or oat milk or soy milk—is naturally high in calcium, a nutrient that promotes bone density, and protein, which contributes to muscle growth.
Non-inclusion of an herb in this list does not imply that it is free of adverse effects. In general, the safety and effectiveness of alternative medicines have not been scientifically proven [1] and remain largely unknown. [2]
Silychristin (also known as silichristin) is a natural product and one of the constituents of silymarin, the standardized, active extract of the fruit of milk thistle, Silybum marianum. [ 1 ] [ 2 ] It is the second most abundant constituent in silymarin, after silybin . [ 3 ]
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