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Ofloxacin has not been shown to have any teratogenic effects at oral doses as high as 810 mg/kg/day (11 times the recommended maximum human dose based on mg/m 2 or 50 times based on mg/kg) and 160 mg/kg/day (four times the recommended maximum human dose based on mg/m 2 or 10 times based on mg/kg) when administered to pregnant rats and rabbits ...
For dogs, a dose ranges from 2.75 - 5.5 mg/kg once a day. The duration of treatment is usually at least five days, longer if there is a concurrent fungal or yeast infection. [ 4 ] Maximum duration of treatment is 30 days.
Continuing the maintenance dose for about 4 to 5 half-lives (t 1/2) of the drug will approximate the steady state level. [1] One or more doses higher than the maintenance dose can be given together at the beginning of therapy with a loading dose. [2] A loading dose is most useful for drugs that are eliminated from the body relatively slowly ...
1,25 dihydroxycholecalciferol 1-Day 1-deamino-8-d-arginine vasopressin 13-cis-retinoic acid 2'-deoxycoformycin 2-amino-6-mercaptopurine 2-amino-6-trifluoromethoxy-benzothiazole 2-CdA 2-chlorodeoxyadenosine 2-PAM 2-propylpentanoic acid 2-propylvaleric acid 2-pyridine aldoxime methochloride 292 MEP 311C90 3M Avagard (Discontinued) 3M Cavilon Skin ...
Clindamycin: Cleocin: Serious staph-, pneumo-, and streptococcal infections in penicillin-allergic patients, also anaerobic infections; clindamycin topically for acne: Possible C. difficile-related pseudomembranous enterocolitis: Binds to 50S subunit of bacterial ribosomal RNA thereby inhibiting protein synthesis. Lincomycin: Lincocin ...
The maximum dose is used, rather than a lower dose, to reduce the number of test subjects (and, among other things, the cost of testing), to detect an effect that might occur only rarely. This type of analysis is also used in establishing chemical residue tolerances in foods. Maximum tolerated dose studies are also done in clinical trials.
Potassium: 0 mg. Olive oil is a source of monounsaturated fats, which are known to support heart health by reducing “bad” cholesterol levels. Olive oil is also a good source of vitamin K, an ...
Of all the drugs in its class, clarithromycin has the best bioavailability at 50%, which makes it amenable to oral administration. Its elimination half-life is about 3 to 4 hours with 250 mg administered every 12 h, but increased to 5 to 7 h with 500 mg administered every 8 to 12 h.
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