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Primodos was a hormone-based pregnancy test, produced by Schering AG, and used in the 1960s and 1970s that consisted of two pills that contained norethisterone (as acetate) and ethinylestradiol. [ 1 ] [ 2 ] It detected pregnancy by inducing menstruation in women who were not pregnant.
Immunologic pregnancy tests were introduced in 1960 when Wide and Gemzell presented a test based on in-vitro hemagglutination inhibition. This was a first step away from in-vivo pregnancy testing [ 42 ] [ 43 ] and initiated a series of improvements in pregnancy testing leading to the contemporary at-home testing. [ 43 ]
Clearblue home pregnancy test system 1985. Clearblue was introduced in 1985 with the launch of the first Clearblue Home Pregnancy Test system, which at the time was owned by Unilever. [4] It was the world’s first “rapid home test” that gave pregnancy test results in 30 minutes and allowed a woman to take a test before going to the doctor. [4]
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Margaret Crane's patent illustration for "Diagnostic Test Device", the first home pregnancy test. Margaret M. Crane (Meg Crane) is an American inventor and graphic designer who created the first at home pregnancy test in 1967 while working at Organon Pharmaceuticals in West Orange, New Jersey. [1]
Before immunological pregnancy tests were developed in the 1960s, women relied on urine-based pregnancy tests using animals, ranging from mice to frogs. [ 1 ] [ 2 ] Advancements in medical technology have enabled women to accurately check their pregnancy status by using 'pee-on-a-stick' pregnancy test kits at home.
Urine-based pregnancy tests detect hCG in the urine, while blood-based pregnancy tests measure the level of hCG in the blood. [5] The presence of hCG in a woman's body indicates that a fertilized egg has implanted in the uterus and the placenta has started to form. 10 days after fertilization, significant hCG can be detected from woman's blood ...
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