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  2. Beano (dietary supplement) - Wikipedia

    en.wikipedia.org/wiki/Beano_(dietary_supplement)

    Beano contains the enzyme α-Galactosidase, specifically one derived from the fungus Aspergillus niger.The enzyme works in the digestive tract to break down the complex or branching sugars (polysaccharides and oligosaccharides) in foods such as legumes (beans and peanuts) and cruciferous vegetables (cauliflower, broccoli, cabbage, and brussels sprouts, among others).

  3. Avalglucosidase alfa - Wikipedia

    en.wikipedia.org/wiki/Avalglucosidase_alfa

    Trial 1 evaluated the benefits and side effects of avalglucosidase alfa, and all four trials evaluated the side effects of avalglucosidase alfa. [9] In trial 1, participants received either avalglucosidase alfa or another drug (called the active comparator) intravenously once every two weeks for 49 weeks. [9]

  4. α-Galactosidase - Wikipedia

    en.wikipedia.org/wiki/Α-Galactosidase

    α-Galactosidase ( EC 3.2.1.22, α-GAL, α-GAL A; systematic name α-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyses the following reaction: [1] Hydrolysis of terminal, non-reducing α- D -galactose residues in α- D -galactosides, including galactose oligosaccharides, galactomannans and galactolipids

  5. Pegunigalsidase alfa - Wikipedia

    en.wikipedia.org/wiki/Pegunigalsidase_alfa

    Pegunigalsidase alfa, sold under the brand name Elfabrio, is an enzyme replacement therapy for the treatment of Fabry disease. [2] [4] It is a recombinant human α-galactosidase-A. [4] It is a hydrolytic lysosomal neutral glycosphingolipid-specific enzyme. [2] The most common side effects are infusion-related reactions, hypersensitivity and ...

  6. Migalastat - Wikipedia

    en.wikipedia.org/wiki/Migalastat

    The most common side effect in clinical trials was headache (in about 10% of people who take it). Less common side effects (between 1 and 10% of people) included unspecific symptoms such as dizziness, fatigue, and nausea, but also depression. Possible rare side effects could not be assessed because of the low number of subjects in the clinical ...

  7. GLA (gene) - Wikipedia

    en.wikipedia.org/wiki/GLA_(gene)

    Two recombinant enzyme replacement therapies are available to functionally compensate for α-galactosidase deficiency. Agalsidase α and β are both recombinant forms of the human α-galactosidase A enzyme and both have the same amino acid sequence as the native enzyme. Agalsidase α and β differ in the structures of their oligosaccharide side ...

  8. β-Galactosidase - Wikipedia

    en.wikipedia.org/wiki/Β-Galactosidase

    [24] [25] and, as a result, the mutant enzyme is able to replace the lacZ β-galactosidase. [26] EbgA and LacZ are 50% identical on the DNA level and 33% identical on the amino acid level. [ 27 ] The active ebg enzyme is an aggregate of ebgA -gene and ebgC-gene products in a 1:1 ratio with the active form of ebg enzymes being an α 4 β4 hetero ...

  9. Alpha-glucosidase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Alpha-glucosidase_inhibitor

    In the colon, bacteria will digest the complex carbohydrates, thereby causing gastrointestinal side effects such as flatulence and diarrhea. Since these effects are dose-related, it is generally advised to start with a low dose and gradually increase the dose to the desired amount. Pneumatosis cystoides intestinalis is another reported side ...

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