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The appearance and perception of a tooth is the result of a complex interaction of factors such as lighting conditions, translucency, opacity, light scattering, gloss and the human eye and brain. [5] Of these, the intrinsic pigmentation of a tooth is the most influential, [4] which in turn is determined by genetic and natural factors. [6]
Tooth whitening or tooth bleaching is the process of lightening the colour of human teeth. [1] Whitening is often desirable when teeth become yellowed over time for a number of reasons, and can be achieved by changing the intrinsic or extrinsic colour of the tooth enamel . [ 2 ]
In dental enamel, fluorosis causes subsurface porosity or hypomineralizations, which extend toward the dentinal-enamel junction as the condition progresses and the affected teeth become more susceptible to staining. Due to diffusion of exogenous ions (e.g., iron and copper), stains develop into the increasingly and abnormally porous enamel. [7]
Symptoms usually appear after a number of years, [5] but may rarely appear within a year. [6] Eye exposure to iron dust can also cause another form of siderosis, "ocular siderosis" or "siderosis bulbi", which can cause eye discoloration, but also eye damage, like cataracts and night blindness. This happens via the corrosive effects of iron. [7] [8]
Iron overload (also known as haemochromatosis or hemochromatosis) is the abnormal and increased accumulation of total iron in the body, leading to organ damage. [1] The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction.
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The first indication of iron poisoning occurs within the first six hours post-ingestion and involves gastrointestinal symptoms including abdominal pain accompanied by nausea and vomiting with or without blood. Due to the disintegration of iron tablets, the stool may appear as black or dark green or gray. [4]
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