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Metronidazole, sold under the brand name Flagyl among others, is an antibiotic and antiprotozoal medication. [10] It is used either alone or with other antibiotics to treat pelvic inflammatory disease, endocarditis, and bacterial vaginosis. [10] It is effective for dracunculiasis, giardiasis, trichomoniasis, and amebiasis. [10]
Depending on the type of surgery and anticipated contamination associated with it, combinations of different agents or different routes of administration (e.g. intravenous and oral antibiotics) might be beneficial in reducing perioperative adverse events. [6] [7] For prophylaxis in surgery, only antibiotics with good tolerability should be used.
Patients should not drink alcohol to prevent disulfiram-like reactions, with symptoms of flushing, tachycardia, palpitations, nausea, vomiting. [51] Alcohol should only be taken at least 3 days after the last dose of metronidazole. [52] [53]
Both medications need a five to ten-day-long course; albendazole is taken once a day, while metronidazole needs to be taken three times a day. The evidence for comparing metronidazole to other alternatives such as mebendazole, tinidazole, or nitazoxanide was felt to be of very low quality. [60]
Patients should be queried about any side effects, missed doses, and completion of therapy. As culture with antibiotic sensitivities is not routinely performed when a H. pylori infection is diagnosed, it is generally recommended that different antibiotics be given at higher doses for 14 days. [2]
Antibiotic synergy is one of three responses possible when two or more antibiotics are used simultaneously to treat an infection. In the synergistic response, the applied antibiotics work together to produce an effect more potent than if each antibiotic were applied singly. [1]
15.8 percent of those taking a 0.5 milligram (mg) dose of semaglutide. 20.3 percent of those taking a 1 mg dose. 44 percent of those taking a 2.4 mg dose.
Many antibiotics are metabolized in the liver. In patients with liver failure, the use of such antibiotics should be restricted in order to avoid toxicity and subsequent overdose. [17] Erythromycin, clindamycin and metronidazole are antibiotics that would require dose adjustments when administered to patients with liver failure.
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