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The pancreas is an organ of the digestive system and endocrine system of vertebrates. In humans, it is located in the abdomen behind the stomach and functions as a gland. The pancreas is a mixed or heterocrine gland, i.e., it has both an endocrine and a digestive exocrine function. [2] 99% of the pancreas is exocrine and 1% is endocrine.
There are about 1 million islets distributed throughout the pancreas of a healthy adult human. While islets vary in size, the average diameter is about 0.2 mm. [5]:928 Each islet is separated from the surrounding pancreatic tissue by a thin, fibrous, connective tissue capsule which is continuous with the fibrous connective tissue that is interwoven throughout the rest of the pancreas.
The pancreas produces and releases important digestive enzymes in the pancreatic juice that it delivers to the duodenum. [24] The pancreas lies below and at the back of the stomach. It connects to the duodenum via the pancreatic duct which it joins near to the bile duct's connection where both the bile and pancreatic juice can act on the chyme ...
Pancreas: 16. Accessory pancreatic duct 17. Pancreatic duct 18. Small intestine: 19. Duodenum 20. Jejunum 21–22. Right and left kidneys The front border of the liver has been lifted up (brown arrow). [2]
The pancreatic duct or duct of Wirsung (also, the major pancreatic duct due to the existence of an accessory pancreatic duct) is a duct joining the pancreas to the common bile duct. This supplies it with pancreatic juice from the exocrine pancreas, which aids in digestion.
Arthropods, especially detritivores in the Order Isopoda, Suborder Oniscidea (), have been shown to be able to store heavy metals in their hepatopancreas. [3] This could lead to bioaccumulation through the food chain and implications for food web destruction, if the accumulation gets high enough in polluted areas; for example, high metal concentrations are seen in spiders of the genus Dysdera ...
Research has shown that beta cells can be differentiated from human pancreas progenitor cells. [37] These differentiated beta cells, however, often lack much of the structure and markers that beta cells need to perform their necessary functions. [37]
The ventral and dorsal pancreatic buds (or pancreatic diverticula) are outgrowths of the duodenum during human embryogenesis.They join to form the adult pancreas.. The proximal portion of the dorsal pancreatic bud gives rise to the accessory pancreatic duct, while the distal portion of the dorsal pancreatic bud and ventral pancreatic bud give rise to the major pancreatic duct.
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