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Like other β adrenergic agonists, they cause smooth muscle relaxation. β 2 adrenergic agonists' effects on smooth muscle cause dilation of bronchial passages, vasodilation in muscle and liver, relaxation of uterine muscle, and release of insulin. They are primarily used to treat asthma and other pulmonary disorders.
LABAs are designed to reduce the need for shorter-acting β 2 agonists such as salbutamol (albuterol), as they have an approximately twelve-hour duration of action, compared to about five hours for salbutamol, making them candidates for sparing high doses of corticosteroids [citation needed] or treating nocturnal asthma and providing ...
It was marketed in 1990. Formoterol, another long-acting β 2-agonist, was marketed shortly after. This long duration of action made the treatment for severe asthma and COPD more convenient for the patients because it is inhaled twice a day. [1] In 2013 an extra long-acting β 2-agonist, vilanterol, was marketed. Its duration of action lasts ...
The goal of asthmatic agents is to reduce asthma exacerbation frequencies and related hospital visits. Anti-asthmatic agents as rescue medications for acute asthma attacks include short-acting β 2-adrenergic receptor agonists (SABA), short-acting muscarinic antagonists (SAMA), systemic glucocorticoids, and magnesium sulfate.
Formoterol, also known as eformoterol, is a long-acting β 2 agonist (LABA) used as a bronchodilator in the management of asthma and chronic obstructive pulmonary disease (COPD). Formoterol has an extended duration of action (up to 12 h) compared to short-acting β 2 agonists such as salbutamol (albuterol), which are effective for 4 h to 6 h.
Beta adrenergic agonists or beta agonists are medications that relax muscles of the airways, causing widening of the airways and resulting in easier breathing. [1] They are a class of sympathomimetic agents, each acting upon the beta adrenoceptors . [ 2 ]
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