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Smoker's melanosis is seen with the naked eye as a brown to black pigmentation of the oral tissue i.e. the gums, [1] cheeks or palate [2] as well as in larynx. [3] [4] It is most often seen in the lower labial gingiva of tobacco users. Most easily it is found in Caucasians, due to their lack of a genetically caused melanin pigmentation. [5] [6]
Gongylonema pulchrum was first named and presented with its own species by Molin in 1857. The first reported case was in 1850 by Dr. Joseph Leidy, when he identified a worm "obtained from the mouth of a child" from the Philadelphia Academy (however, an earlier case may have been treated in patient Elizabeth Livingstone in the seventeenth century [2]).
For example, Addison's disease causes hyperpigmentation in the mouth and may be noticed during an exam followed alongside other systemic symptoms. An oral biopsy alongside other relevant tests (i.e. bloods) should be taken and confirmed for diagnosis for any type of oral melanosis which you suspect to be caused by an underlying disease.
Diabetes: "Gum disease and diabetes have a bidirectional relationship, meaning that gum disease can make it harder to control blood sugar levels, and uncontrolled diabetes can increase the risk of ...
The life of the parasite can be traced through the black fly and the human hosts in the following steps: [13] [14] A Simulium female black fly takes a blood meal on an infected human host and ingests microfilaria. The microfilaria enter the black fly's gut and thoracic flight muscles, progressing into the first larval stage (J1.).
Leukoedema lesions disappear when the mucosa is stretched, which helps to differentiate it from other white lesions in the mouth. [2] The differential diagnosis is with leukoplakia , oral candidiasis , oral lichen planus , white sponge nevus , morsicatio buccarum , [ 3 ] hereditary benign intraepithelial dyskeratosis and dyskeratosis congenita.
Infection usually begins in the mouth or nose and enters the central nervous system via the eyes. [5] If the fungal infection begins in the nose or sinus and extends to brain, symptoms and signs may include one-sided eye pain or headache, and may be accompanied by pain in the face, numbness, fever, loss of smell, a blocked nose or runny nose.
The gums are red, friable, or sometimes granular, and sometimes bleed easily if traumatised. [6] The normal stippling is lost. [7] There is not usually any loss of periodontal attachment. [6] In a few cases a sore mouth can develop, and if so pain is sometimes made worse by toothpastes, or hot or spicy food. [7]
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