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Erythema annulare centrifugum (EAC), is a descriptive term for a class of skin lesion [2] presenting redness in a ring form (anulare) that spreads from a center (centrifugum). It was first described by Darier in 1916.
The culprit can be both a prescription drug or an over-the-counter medication. Examples of common drugs causing drug eruptions are antibiotics and other antimicrobial drugs, sulfa drugs, nonsteroidal anti-inflammatory drugs (NSAIDs), biopharmaceuticals, chemotherapy agents, anticonvulsants and psychotropic drugs.
Annular erythema of infancy (AEI) consists of self-limited eruptions of erythematous, annular to polycyclic patches and plaques. It is an idiopathic figurate erythema. [1] Over several days, a single lesion disappears without leaving behind any scale or hyperpigmentation. Mostly affecting the trunk, face, and extremities, this rash has no symptoms.
Molluscum contagiosum (MC), sometimes called water warts, is a viral infection of the skin that results in small raised pink lesions with a dimple in the center. [1] They may become itchy or sore, and occur singularly or in groups. [1]
Figurate erythema is a form of erythema (reddening of the skin) that presents in a ring or an arc shape. An example is erythema marginatum. [1] Classical types include: [2] Erythema annulare centrifugum; Erythema marginatum rheumaticum; Erythema chronicum migrans; Erythema gyratum repens
The diagnosis of AGEP may be forthright in typical cases in which an individual: has taken a drug known to cause the disorder; develops multiple sterile pustules overlying large areas of red swollen skin starting a few days after initial drug intake; and has a histology of biopsied lesions that shows pustules just below the skin's Stratum ...
The treatment is based upon the hypothesis that parasitic mites of the genus Demodex play a role in rosacea. [38] In a clinical study, ivermectin reduced lesions by 83% over 4 months, as compared to 74% under a metronidazole standard therapy. [39] Quassia amara extract at 4% demonstrated to have clinical efficacy for rosacea. [40]
Erythema multiforme (EM) is generally considered a separate condition. [6] Treatment typically takes place in hospital such as in a burn unit or intensive care unit. [3] [7] Efforts include stopping the cause, pain medication, and antihistamines. [3] [4] Antibiotics, intravenous immunoglobulins, and corticosteroids may also be used.