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Adderall and Mydayis [11] are trade names [note 2] for a combination drug containing four salts of amphetamine.The mixture is composed of equal parts racemic amphetamine and dextroamphetamine, which produces a (3:1) ratio between dextroamphetamine and levoamphetamine, the two enantiomers of amphetamine. [13]
The drugs include Adderall, Vyvanse and generic amphetamines, such as dextroamphetamine. The link between amphetamines and psychosis isn’t new. Amphetamines increase levels of dopamine in the brain.
In rodents and primates, sufficiently high doses of amphetamine cause dopaminergic neurotoxicity, or damage to dopamine neurons, which is characterized by dopamine terminal degeneration and reduced transporter and receptor function. [169] [170] There is no evidence that amphetamine is directly neurotoxic in humans.
Dopaminergic antipsychotics affect dopamine neurons by binding to postsynaptic dopamine receptors, where they function as receptor antagonists. [111] In contrast, ADHD stimulants are indirect agonists of postsynaptic dopamine receptors; [ 111 ] in other words, these stimulants increase levels of synaptic dopamine, which then binds to ...
Plus, there’s the question of addiction: If you stop taking stimulant medications (like Adderall) quickly after a period of chronic misuse or overuse, you may experience withdrawal symptoms.
When it comes to Wellbutrin vs Adderall, these two medications do have some similarities, including that they both affect the brain’s supply of norepinephrine and dopamine.
Also, the production, distribution, sale, and possession of methamphetamine is restricted or illegal in many other countries due to its placement in schedule II of the United Nations Convention on Psychotropic Substances treaty. [144] [145] In contrast, levomethamphetamine is an over-the-counter drug in the United States. [note 1]
Adderall and Ritalin, the study drugs of choice in universities around the country, will let you write a physics paper from sundown to sunup. First synthesized in the 1940s to treat fatigue ...