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[6] [5] Fluconazole is in the azole antifungal family of medication. [5] It is believed to work by affecting the fungal cellular membrane. [5] Fluconazole was patented in 1981 and came into commercial use in 1988. [7] It is on the World Health Organization's List of Essential Medicines. [8] Fluconazole is available as a generic medication. [5]
Antifungal resistance is a One Health concern, driven by multiple extrinsic factors, including extensive fungicidal use, overuse of clinical antifungals, environmental change and host factors. [1] Like resistance to antibacterials, antifungal resistance can be driven by antifungal use in agriculture.
While men are less likely to develop osteoporosis, it is possible and has been occurring more often in recent years in men over age 65. “Most men should aim for 1,000 - 1,200mg of calcium per ...
In hospitalized patients who develop candidemia, age is an important prognostic factor. Mortality following candidemia is 50% in patients aged ≥75 years and 24% in patients aged <75 years. [75] Among individuals being treated in intensive care units, the mortality rate is about 30–50% when systemic candidiasis develops. [76]
Fosfluconazole (INN Tooltip International Nonproprietary Name) is a water-soluble phosphate prodrug of fluconazole [1] — a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
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Some might need two, a year apart, depending on their personal risk factors. “The peak in serious invasive pneumococcal infections occurs earlier in the Black population” at about 55 to 60, he ...
Itraconazole also showed activity in a phase II trial in men with non-small cell lung cancer when it was combined with the chemotherapy agent, pemetrexed. [ 15 ] [ 16 ] [ 17 ] A recent review also highlights its use topically and orally in conjunction with other chemotherapeutic agents for advanced and metastatic basal cell carcinomas that ...
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