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Synthetic oxytocin, sold under the brand name Pitocin among others, is a medication made from the peptide oxytocin. [ 6 ] [ 7 ] As a medication, it is used to cause contraction of the uterus to start labor , increase the speed of labor , and to stop bleeding following delivery . [ 6 ]
Oxytocin/ergometrine (trade name Syntometrine) is an obstetric combination drug. The components are synthetically produced oxytocin , a human hormone produced in the hypothalamus , and ergometrine , an alpha-adrenergic , dopaminergic and serotonin (5-HT 2 ) receptor agonist.
This is a procedure that relies on endogenous release of oxytocin following nipple stimulation, and is conducted by the patient. The nurse instructs the patient on the procedure, as follows. One nipple is massaged gently through clothing until a contraction begins, or for a maximum of 2 minutes.
Oxytocin receptor antagonist Safer than both nifedipine and beta agonists; As effective as nifedipine and more effective than beta agonists. [29] Fewer side effects than β 2 agonists. [30] Although not FDA approved in the US, atosiban was developed specifically to delay preterm labor. [31] No current contraindications No maternal adverse ...
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. [4] Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth.
Carbetocin has been approved for use immediately following an elective Cesarean section when a local or spinal anesthesia has been used. [8] Since the uterus cannot contract on its own following incision during a Cesarean section, exogenous administration of oxytocin or an analog is necessary to restore uterine tone and prevent hemorrhage.
Demoxytocin (brand names Sandopart, Odeax, Sandopral), also known as desaminooxytocin or deaminooxytocin, as well as 1-(3-mercaptopropanoic acid)oxytocin ([Mpa 1]OT), is an oxytocic peptide drug that is used to induce labor, [1] promote lactation, [2] and to prevent and treat puerperal (postpartum) mastitis (breast inflammation). [3]
Additionally, severe hypercholesterolemia and hypertriglyceridemia are also contraindications, but the evidence showing that combined oral contraceptive pills lead to worse outcomes in this population is weak. [37] [40] Obesity is not considered to be a contraindication to taking combined oral contraceptive pills. [40]