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Synthetic oxytocin, sold under the brand name Pitocin among others, is a medication made from the peptide oxytocin. [ 6 ] [ 7 ] As a medication, it is used to cause contraction of the uterus to start labor , increase the speed of labor , and to stop bleeding following delivery . [ 6 ]
Oxytocin is a peptide hormone and neuropeptide normally produced in the hypothalamus and released by the posterior pituitary. [4] Present in animals since early stages of evolution, in humans it plays roles in behavior that include social bonding, love, reproduction, childbirth, and the period after childbirth.
Avoiding first-pass metabolism allows more of the drug to be available for treatment. Gastrointestinal discomfort and digestive side-effects can also be avoided by IN dosage. IN delivery allows OT to cross the blood brain barrier, expediting the drug to the central nervous system and cerebrospinal fluid. The blood-brain-barrier normally ...
There are also risks associated with membrane sweeping. The risks include irregular contractions, bleeding, and in 1 out of every 10 women an amniotic sac rupture, which can lead to a formal induction within 24 hours of the rupture if labor hasn't been induced. [5] The use of intrauterine catheters are also indicated.
As she began to push, her daughter’s shoulders became stuck in her birth canal, a dangerous emergency called shoulder dystocia. Baker managed to dislodge the baby, Suarez said, who survived.
Oxytocin/ergometrine (trade name Syntometrine) is an obstetric combination drug.The components are synthetically produced oxytocin, a human hormone produced in the hypothalamus, and ergometrine, an alpha-adrenergic, dopaminergic and serotonin (5-HT 2) receptor agonist.
Misoprostol can cause unpleasant side effects such as very high body temperatures and shivering. [27] Lower doses of misoprostol appear to be safer and cause less side effects. [27] Giving oxytocin in a solution of saline into the umbilical vein is a method of administering the drug directly to the placental bed and uterus. [28]
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