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Blood tests for lipase may be used to help investigate and diagnose acute pancreatitis and other disorders of the pancreas. [32] Measured serum lipase values may vary depending on the method of analysis. [citation needed] Lipase assist in the breakdown of fats in those undergoing pancreatic enzyme replacement therapy (PERT).
In many studies that have been conducted, hepatic lipase is also closely related to obesity. In one test, an experiment was created by Cedó et al. where mouse cells were created to have a mutated HL protein that has lost its function. They found that a build-up of triglyceride levels led to nonalcoholic fatty liver disease.
Liver function tests (LFTs or LFs), also referred to as a hepatic panel or liver panel, are groups of blood tests that provide information about the state of a patient's liver. [1] These tests include prothrombin time (PT/INR), activated partial thromboplastin time (aPTT), albumin , bilirubin (direct and indirect), and others.
If the lipase level is about 2.5 to 3 times that of amylase, it is an indication of pancreatitis due to alcohol. [14] Serum lipase is more sensitive and specific than serum amylase in the diagnosis of acute pancreatitis, and is the preferred test in the diagnosis. [15] [16]
A lipid profile or lipid panel is a panel of blood tests used to find abnormalities in blood lipid ( such as cholesterol and triglycerides) concentrations. [not verified in body] The results of this test can identify certain genetic diseases and can determine approximate risks for cardiovascular disease, certain forms of pancreatitis, and other diseases.
In laboratory test it is expected that the total serum concentration of cholesterol, low density lipoproteins, and triglycerides will be high and the serum concentration of high density lipoproteins are low for a positive result of acid lipase disease. [6] The genetic tests done are: [6] Single-gene testing; A multigene panel
Quantitative fecal fat tests measure and report an amount of fat. This is usually done over a period of three days, the patient collecting all of their feces into a container. The container is thoroughly mixed to homogenize the feces, without using specific mixer equipment. A small sample from the feces is collected.
Lipase assays are done using a lipid agar with a spirit blue dye. If the bacteria has lipase, a clear streak will form in the agar, and the dye will fill the gap, creating a dark blue halo around the cleared area. Staphylococcus epidermidis results in a positive lipase assay. [2]