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Basaloid forms of lung carcinoma were first described in the peer-reviewed medical literature by Dr. Elisabeth Brambilla and her colleagues in 1992. [11] They were first recognized as distinct clinicopathological variants of both squamous cell and large cell lung cancers in 1999, within the third revision of the World Health Organization lung tumor typing and classification scheme.
Large-cell lung carcinoma (LCLC), or large-cell carcinoma (LCC) in short, is a heterogeneous group of undifferentiated malignant neoplasms that lack the cytologic and architectural features of small cell carcinoma and glandular or squamous differentiation. [1]
The true incidence and prevalence of basaloid squamous cell lung carcinoma remains unknown, but this form of lung cancer is considered relatively uncommon. [17] In one of the largest studies of this particular variant, Moro-Sibilot and co-workers found a 6.3% prevalence of Bas-SqCC among 1,418 consecutive NSCLC patients at their institution. [7]
M8078/3 Squamous cell carcinoma with horn formation; M8080/2 Queyrat erythroplasia (C60._) M8081/2 Bowen disease (C44._) Intraepidermal squamous cell carcinoma, Bowen type (C44._) M8082/3 Lymphoepithelial carcinoma Lymphoepithelioma; Lymphoepithelioma-like carcinoma; Schmincke tumor (C11._) M8083/3 Basaloid squamous cell carcinoma
Giant-cell carcinoma of the lung; Large-cell lung carcinoma; Large cell lung carcinoma with rhabdoid phenotype; Laryngeal cancer; Mesothelioma; Non-small cell lung cancer; Non-small cell lung carcinoma; Pleuropulmonary blastoma; Sarcomatoid carcinoma of the lung; Small cell lung cancer; Squamous-cell carcinoma of the lung; Thymoma and thymic ...
Basaloid large cell carcinoma of the lung; Basaloid squamous cell lung carcinoma; Jim Bishop (doctor) British Doctors Study; Adenocarcinoma in situ of the lung; C ...
When associated with the lung, it is typically a centrally located large-cell cancer (non-small-cell lung cancer). It often has a paraneoplastic syndrome causing ectopic production of parathyroid hormone-related protein, resulting in hypercalcemia, but paraneoplastic syndrome is more commonly associated with small-cell lung cancer. It is ...
Lung cancers are now considered a large and extremely heterogeneous family of neoplasms [4] that feature widely varying genetic, biological, and clinical characteristics. . About 50 different lung cancer variants are recognized under the 2004 revision of the World Health Organization ("WHO-2004") histological typing system, the most widely recognized and used lung cancer classification sche