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An expectorant increases bronchial secretions and mucolytics help loosen thick bronchial secretions. Expectorants reduce the thickness or viscosity of bronchial secretions, thus increasing mucus flow that can be removed more easily through coughing. Mucolytics break down the chemical structure of mucus molecules.
Mucokinetics, or mucolytics, are a class of drugs which aid in the clearance of mucus from the airways, lungs, bronchi, and trachea. Examples are carbocisteine , ambroxol , and bromhexine . Expectorants are substances claimed to make coughing easier while enhancing the production of mucus and phlegm.
Decongestants and expectorants are both effective at treating different cold and allergy symptoms. Decongestants are a type of medicine that can provide short-term relief for a blocked or stuffy ...
Bromhexine is intended to support the body's mechanisms for clearing mucus from the respiratory tract.It is secretolytic, increasing the production of serous mucus in the respiratory tract, which makes the phlegm thinner and less viscous.
This mechanism is most likely responsible for the mucolytic effects of the drug, but may also explain the reported activity in Gaucher and Parkinson's disease. Both ambroxol and its parent drug bromhexine have been shown to induce autophagy in several cell types, and ambroxol was shown to potentiate rifampicin therapy in a model of tuberculosis ...
Carbocisteine, also called carbocysteine, is a mucolytic that reduces the viscosity of sputum and so can be used to help relieve the symptoms of chronic obstructive pulmonary disorder (COPD) and bronchiectasis by allowing the sufferer to bring up sputum more easily.
Acetylcysteine exhibits mucolytic properties, meaning it reduces the viscosity and adhesiveness of mucus. This therapeutic effect is achieved through the cleavage of disulfide bonds [ 31 ] within mucoproteins (strongly cross-linked mucins ), [ 32 ] thereby decreasing the mucus viscosity and facilitating its clearance from the respiratory tract.
Guaifenesin might act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi via stimulation of the gastric mucosa. . This stimulation leads to an increased parasympathetic activity in the respiratory tract via the so-called gastro-pulmonary reflex, although some in vitro studies suggested that it might also act directly on the ...