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A prokinetic agent (also prokineticin, gastroprokinetic agent, gastrokinetic agent or propulsive) is a type of drug which enhances gastrointestinal motility by increasing the frequency or strength of contractions, but without disrupting their rhythm. [1]
The gastrocolic reflex or gastrocolic response is a physiological reflex that controls the motility, or peristalsis, of the gastrointestinal tract following a meal. It involves an increase in motility of the colon consisting primarily of giant migrating contractions, in response to stretch in the stomach following ingestion and byproducts of digestion entering the small intestine. [1]
Temperature, peristalsis, bile secretion, secretion of saliva, stomach and pancreas enzymes are all fully adjustable. The TIM systems are being used to study the behavior of oral products during transit through the stomach, the small intestine and large intestine.
Peristalsis (/ ˌ p ɛr ɪ ˈ s t æ l s ɪ s / PERR-ih-STAL-siss, US also /-ˈ s t ɔː l-/- STAWL-) [1] is a type of intestinal motility, characterized by radially symmetrical contraction and relaxation of muscles that propagate in a wave down a tube, in an anterograde direction. Peristalsis is progression of coordinated contraction of ...
Peristalsis is the rhythmic contraction of muscles that begins in the esophagus and continues along the wall of the stomach and the rest of the gastrointestinal tract. This initially results in the production of chyme which when fully broken down in the small intestine is absorbed as chyle into the lymphatic system .
A stomach rumble, also known as a bowel sound, peristaltic sound, abdominal sound, bubble gut or borborygmus (pronounced / ˌ b ɔːr b ə ˈ r ɪ ɡ m ə s /; plural borborygmi), is a rumbling, growling or gurgling noise produced by movement of the contents of the gastrointestinal tract as they are propelled through the small intestine by a series of muscle contractions called peristalsis. [1]
The gastroileal reflex is stimulated by the presence of food in the stomach and gastric peristalsis. Initiation of the reflex causes peristalsis in the ileum and the opening of the ileocecal valve (which allows the emptying of the ileal contents into the large intestine, or colon). [ 1 ]
Lactulose works by the osmotic effect, which retains water in the colon; lowering the pH through bacterial fermentation to lactic, formic, and acetic acids; and increasing colonic peristalsis. Lactulose is also indicated in portal-systemic encephalopathy .
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