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In regards to drug delivery, coiled-coil domains would help overcome some of the hazards of chemotherapeutic drugs, by keeping them from leaking into healthy tissue as they are transported to their target. Coiled-coil domains can be made to bind to specific proteins or cell surface markers, allowing for more precise targeting in drug delivery. [35]
A new report by the Clean Label Project has found that protein powders may contain something other than muscle-building nutrients: lead and cadmium, both of which are toxic.. The national ...
Coiled-coil research began in 1953 when Dr. Francis Crick first reported on the theory behind the packing formation of α-helices in fibrous proteins at the time, which he proposed to consist of alpha helices composed of heptad repeats, or seven-residue repeats (a-b-c-d-e-f-g), whereby 2 or more alpha helices twist around each other similar to the strands of a rope. [2]
WD Repeat and Coiled-coiled containing protein (WDCP) is a protein which in humans is encoded by the WDCP gene. The function of the protein is not completely understood, but WDCP has been identified in a fusion protein with anaplastic lymphoma kinase found in colorectal cancer . [ 5 ]
Coiled-Coil Domain Containing protein 82 (CCDC82) is a protein that in humans, is encoded for by the gene of the same name, CCDC82. The CCDC82 gene is expressed in nearly all of human tissues at somewhat low rates. As of today, there are no patents involving CCDC82 and the function remains unknown.
A new Clean Label Project report suggests some protein powders contain heavy metals lead and cadmium. See which ones are safe here, plus what an expert advises. ‘Elevated Levels’ of Heavy ...
G βγ expression is universal throughout almost all the cells of the body so any agent acting to inhibit this subunit could elicit numerous side effects. Small molecule inhibitors that target the coupling of G βγ to specific effectors and do not interfere with normal G protein cycling/ heterotrimeric formation, have the potential to work as ...
Coiled-coil domain 47 (CCDC47) is a gene located on human chromosome 17, specifically locus 17q23.3 which encodes for the protein PAT complex subunit CCDC47. The protein itself contains coiled-coil domains , the SEEEED superfamily, a domain of unknown function (DUF1682) and a transmembrane domain.